Figure 1.

Schematic representation of the rabbit cardiomyocyte model, showing how a transversal cell segment is divided into individual domains. Calcium enters the cell via L-type channels in the membrane domains (1 and 18) and diffuses toward the cell center. Each domain has its own sarcoplasmic reticulum and calcium release units, while the membrane domains also include membrane currents and sub-sarcolemmal spaces.