Table 3.
Effects of individually changing the RAP parameters in each of the 16 models of the control population.
Population | Normal | Alternans | Silencing | Alt+Silenc | Other |
---|---|---|---|---|---|
Control | 100 | 0 | 0 | 0 | 0 |
GCaL(1) | 0 | 0 | 100 | 0 | 0 |
ImaxNCX(2) | 37.5 | 31.25 | 18.75 | 6.25 | 6.25 |
ImaxNaK(3) | 37.5 | 0 | 62.5 | 0 | 0 |
Serca2a density (4) | 87.5 | 12.5 | 0 | 0 | 0 |
RyR Po (5) | 62.5 | 0 | 37.5 | 0 | 0 |
RyR density (6) | 0 | 0 | 31.25 | 0 | 68.75 |
Calcium buffering strength (7) | 100 | 0 | 0 | 0 | 0 |
Full RAP remodeling (8) | 0 | 0 | 100 | 0 | 0 |
Each row corresponds to one of the eight RAP populations, and the values correspond to % incidence of each type of calcium wave patterns in the population.