TABLE 2.

Correlations between MRI variables and plasma angiotensins in AD patients and controls.

	Plasma Ang II	Plasma Ang-(1–7)	Ang-(1–7)/Ang II ratio
	Spearman’s rho coefficient (95% confidence interval)
AD patients
Hippocampus volume	−0.05 (−0.57 to 0.5), p = 0.868	0.13 (−0.44 to 0.63), p = 0.64	0.19 (−0.39 to 0.66), p = 0.512
Medial temporal cortex volume	−0.21 (−0.67 to 0.37), p = 0.464	0.02 (−0.52 to 0.56), p = 0.928	0.26 (−0.32 to 0.7), p = 0.357
Precuneus cortical volume	−0.43 (−0.79 to 0.14), p = 0.124	−0.21 (−0.67 to 0.37), p = 0.463	0.3 (−0.28 to 0.72), p = 0.295
White matter hypointensities volume	0.464 (−0.1 to 0.8), p = 0.097	0.56 (0.03 to 0.84), p = 0.038	−0.05 (−0.58 to 0.49), p = 0.844
Controls
Hippocampus volume	0.09 (−0.49 to 0.62), p = 0.751	−0.36 (−0.77 to 0.24), p = 0.217	−0.38 (−0.77 to 0.22), p = 0.196
Medial temporal cortex volume	−0.02 (−0.57 to 0.54), p = 0.945	−0.45 (−0.8 to 0.15), p = 0.123	−0.36 (−0.77 to 0.24), p = 0.214
Precuneus cortical volume	0.22 (−0.39 to 0.69), p = 0.47	−0.09 (−0.62 to 0.49), p = 0.751	−0.32 (−0.75 to 0.29), p = 0.28
White matter hypointensities volume	−0.16 (−0.66 to 0.43), p = 0.591	−0.23 (−0.70 to 0.37), p = 0.437	−0.4 (−0.78 to 0.21), p = 0.176

Significant findings (p < 0.05) are in bold.