Fig. 5.

PILI - RSN analysis. The differences between the PILIs in LSD and PCB are shown on an RSN level. For all the nodes forming part of one RSN the Cohen's d value was calculated based on the mean and standard deviation over nodes in each state, indicating the standardized mean difference between the PILIs of each RSN in LSD and PCB. This was done for each of the 7 RSNs. The RSNs were ordered for each scanning condition (rest, rest with music, rest after music) by Cohen's d values, where darker colours indicate larger differences in PILI between the LSD and PCB conditions. The white area, which represents the corpus callosum and the subcortical structures, is to be discarded. It should be noted that the differences between PILI values in LSD and PCB state models for each RSN have found to be statistically significant in the rest and the rest with music condition. In the rest after music condition only 2 out of 7 networks (limbic network and DMN) show statistically significant differences (see Supplementary Table S4).