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The presence of high-risk histological features in the tumours of the two cases
| Histological features | Case one - well differentiated | Case two - poorly differentiated |
|---|---|---|
| Pattern of invasion | Cohesive | Non-cohesive |
| Tumour depth | 4.5 mm | 10 mm+ |
| Perineural invasion | No | Yes |
| Invasion of vessels | No | Yes |
