Table 2.
Results of multivariate analysis predicting readmission to hospital in patients with decompensated cirrhosis
| 30-day readmission | 90-day readmission | 180-day readmission | ||||
|---|---|---|---|---|---|---|
| Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | |
| Age, per 10-year increase | 1.08 (1.05–1.10) | < 0.01 | 1.11 (1.09–1.13) | < 0.01 | 1.12 (1.10–1.14) | < 0.01 |
| Female gender | 0.79 (0.74–0.85) | < 0.01 | 0.70 (0.66–0.74) | < 0.01 | 0.78 (0.74–0.82) | < 0.01 |
| Insurance coverage | ||||||
| Private | 1.0 | — | 1.0 | — | 1.0 | — |
| Medicare | 1.09 (0.99–1.21) | 0.09 | 1.08 (0.99–1.17) | 0.06 | 1.08 (0.99–1.18) | 0.06 |
| Medicaid | 1.74 (1.56–1.94) | < 0.01 | 1.79 (1.69–1.89) | < 0.01 | 1.81 (1.66–1.97) | < 0.01 |
| Other | 1.12 (0.99–1.26) | 0.07 | 1.14 (1.08–1.20) | < 0.01 | 1.16 (1.05–1.28) | < 0.01 |
| 1st zip code income quartile | 1.32 (1.17–1.47) | < 0.01 | 1.21 (1.14–1.30) | < 0.01 | 1.32 (1.20–1.44) | < 0.01 |
| 2nd zip code income quartile | 1.25 (1.13–1.38) | < 0.01 | 1.19 (1.12–1.28) | < 0.01 | 1.30 (1.19–1.41) | < 0.01 |
| 3rd zip code income quartile | 1.08 (0.97–1.20) | 0.15 | 1.08 (1.02–1.15) | < 0.01 | 1.14 (1.05–1.24) | < 0.01 |
| 4th zip code income quartile | 1.0 | — | — | — | 1.0 | — |
| Discharge location | ||||||
| Home | 1.0 | — | 1.0 | — | 1.0 | — |
| Skilled nursing facility | 0.89 (0.81–0.97) | 0.01 | 0.86 (0.81–0.91) | < 0.01 | 0.77 (0.71–0.83) | < 0.01 |
| Hospice/home care | 1.09 (1.00–1.19) | 0.04 | 1.05 (0.99–1.12) | 0.09 | 0.97 (0.90–1.05) | 0.50 |
| Other | 1.61 (1.41–1.83) | < 0.01 | 1.36 (1.24–1.48) | < 0.01 | 1.33 (1.19–1.49) | < 0.01 |
| State resident | 1.14 (0.90–1.45) | 0.28 | 1.35 (1.15–1.58) | < 0.01 | 1.28 (1.02–1.61) | 0.03 |
| Varices/variceal bleed | 4.60 (4.27–4.93) | < 0.01 | 5.66 (5.23–6.12) | < 0.01 | 6.83 (6.12–7.55) | < 0.01 |
| Ascites | 82.8 (71.1–96.5) | < 0.01 | 86.5 (78.7–95.9) | < 0.01 | 60.6 (53.7–68.3) | < 0.01 |
| Hepatic encephalopathy | 1.31 (1.16–1.48) | < 0.01 | 1.37 (1.26–1.50) | < 0.01 | 1.31 (1.17–1.47) | < 0.01 |
| Spontaneous bacterial peritonitis | 0.87 (0.69–1.10) | 0.25 | 0.90 (0.78–1.05) | < 0.01 | 1.01 (0.83–1.23) | 0.94 |
| Hepatorenal syndrome | 0.94 (0.83–1.06) | 0.31 | 0.81 (0.74–0.88) | < 0.01 | 0.73 (0.65–0.82) | < 0.01 |
| Hyponatremia | 1.30 (1.20–1.40) | < 0.01 | 1.20 (1.14–1.27) | < 0.01 | 1.15 (1.08–1.23) | < 0.01 |
| Hepatocellular carcinoma | 3.19 (2.74–3.72) | < 0.01 | 5.94 (5.11–6.89) | < 0.01 | 3.19 (2.78–3.65) | < 0.01 |
| Do Not Resuscitate status | 0.40 (0.35–0.45) | < 0.01 | 0.38 (0.35–0.42) | < 0.01 | 0.36 (0.32–0.40) | < 0.01 |
| Alcohol use | 1.66 (1.52–1.81) | < 0.01 | 1.80 (1.68–1.92) | < 0.01 | 1.93 (1.80–2.08) | < 0.01 |
| Rural hospital | 0.76 (0.67–0.87) | < 0.01 | 0.78 (0.72–0.84) | < 0.01 | 0.79 (0.71–0.88) | < 0.01 |
| Teaching hospital | 1.07 (0.98–1.17) | 0.11 | 1.18 (1.09–1.26) | < 0.01 | 1.09 (1.01–1.17) | 0.04 |
All variables present in the model are displayed except for the Elixhauser comorbidity indices, which are displayed in Table S1. Area under the curve of model is 0.91. CI, confidence interval.