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. 2021 Feb 1;106(5):1377–1388. doi: 10.1210/clinem/dgaa981

Table 3.

Changes in body composition measures in the active vitamin D3 group, stratified by 2-year 25(OH)D levels above/below median

2-year total 25(OH)D level 2-year free 25(OH)D level
<median (97 nmol/L) N = 175 ≥median N = 185 P-value <median (21pmol/L) N = 178 ≥median N = 182 P-value
Weight, mean (SD), kg Baseline 85.3 (16.7) 79.0 (16.0) 87.1 (17.7) 77.0 (13.9)
% change −0.01% −1.11% 0.12 −0.42% −0.70% 0.76
BMI, mean (SD), kg/m2 Baseline 29.2 (5.4) 27.3 (4.9) 30.0 (5.9) 26.5 (3.8)
% change 0.39% −0.46% 0.21 0.04% −0.11% 0.83
Waist circumference, mean (SD), cm Baseline 101.3 (14.3) 96.0 (14.9) 102.8 (15.0) 94.4 (13.4)
% change −0.59% −2.16% 0.09 −1.00% −1.78% 0.43
% Body fat, mean (SD) Baseline 36.5 (8.6) 35.7 (8.3) 37.8 (9.0) 34.5 (7.5)
% change −0.56% −2.01% 0.06 −1.21% −1.36% 0.93
FMI, mean (SD), kg/m2 Baseline 10.7 (4.2) 9.7 (3.8) 11.4 (4.7) 9.0 (2.9)
% change −0.10% −2.14% 0.17 −0.91% −1.29% 0.92
Fat to lean mass ratio, mean (SD) Baseline 0.64 (0.25) 0.61 (0.23) 0.68 (0.27) 0.58 (0.20)
% change −1.33% −3.12% 0.15 −2.23% −2.20% 0.83
VAT area, mean (SD), cm2 Baseline 179 (72) 154 (71) 190 (76) 143 (60)
% change 2.16% −1.87% 0.04 0.87% −0.51% 0.58
Truncal fat mass, mean (SD), kg Baseline 16.2 (6.1) 14.4 (5.6) 17.3 (6.5) 13.3 (4.5)
% change −0.22% −3.54% 0.07 −1.28% −2.45% 0.69
Truncal-to-limb fat ratio, mean (SD) Baseline 1.26 (0.31) 1.20 (0.30) 1.28 (0.32) 1.18 (0.28)
% change −0.33% −1.16% 0.48 −0.29% −1.22% 0.29
LMI, mean (SD), kg/m2 Baseline 16.9 (2.4) 16.0 (2.3) 17.0 (2.4) 15.9 (2.2)
% change 1.11% 0.85% 0.53 1.23% 0.72% 0.19
ALM, mean (SD), kg Baseline 21.3 (5.0) 19.7 (5.0) 21.2 (5.1) 19.8 (5.0)
% change −0.04% 0.22% 0.62 0.08% 0.09% 0.89
ALM/BMI, mean (SD) Baseline 0.74 (0.18) 0.73 (0.18) 0.72 (0.18) 0.75 (0.18)
% change −0.58% 0.80% 0.01 −0.08% 0.29% 0.43

Results are adjusted for age, sex, and race/ethnicity.