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. 2021 Apr 12;21(6):468. doi: 10.3892/ol.2021.12729

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Copyright: © Abeni et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Methylation levels of keratin filament genes in FBC compared with MBC. Dot plots were generated by Partek Genomics Suite and represent the DMRs associated with GO term ‘GO: 0045095: Keratin filament’ in FBC compared with MBC. Each graph refers to a specific KRT gene and KRTAP genes. Within a graph a point represents the Δ methylation value of a DMR for a given breast cancer case. FBC cases are shown in red and MBC cases are shown in blue. A total of two DMRs were detected for the KRT78 gene, indicated as (i) and (ii). The numbers on the y-axis are Δ methylation values. DMR, differentially methylated region; FBC, female breast cancer; GO, Gene Ontology; KRT, keratin; KRTAP, keratin-associated protein; MBC, male breast cancer.