Table 3.
Linear regression analysis of pre- and intraoperative factors associated with surgery-related loss of muscle quantity
| Factors | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| B (95% CI) | P-value | B (95% CI) | P-value | |
| Age (per 1 year increase) | 0.036 (− 0.161–0.234) | 0.716 | ||
| Gender (male) | − 3.240 (− 6.928–0.448) | 0.085* | ||
| BMI (per kg/m2) | 0.132 (− 1.063–1.326) | 0.828 | ||
| CEAa (per μg/L) | − 0.007 (− 0.029–0.016) | 0.553 | ||
| ASA grade | ||||
| I | ||||
| II | − 2.099 (− 6.815–2.618) | 0.380 | ||
| III | 5.417 (− 2.078–12.911) | 0.155 | ||
| Comorbidity | ||||
| Diabetes | 10.778 (3.466–18.091) | 0.004 | 11.173 (3.937–18.408) | 0.003 |
| Chronic obstructive pulmonary disease | 7.307 (− 0.717–15.331) | 0.074* | 7.948 (0.165–15.731) | 0.045 |
| Surgery | ||||
| Open resection (versus laparoscopic) | 1.314 (− 4.022–6.649) | 0.627 | ||
| Major (versus minor) | − 1.465 (− 4.934–2.003) | 0.405 | ||
| Resection + RFA ( versus only resection) | 2.419 (− 1.962–6.799) | 0.277 | ||
| Blood loss (per ml) | − 0.001 (− 0.003–0.001) | 0.383 | ||
| Operation time (per min) | − 0.002 (− 0.026–0.030) | 0.884 | ||
BMI body mass index, CEA carcinoembryonic antigen, ASA American Society of Anesthesiologists, RFA radiofrequency ablation
Bold variables were considered statistically significant (P < 0.05). *Variables that were taken into the multivariable analysis (P < 0.010)
a28 patients missing