Table 4.
Logistic regression analysis of pre- and intraoperative factors associated with surgery-related loss of muscle quality
| Factors | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Age (per 1 year) | 1.059 (1.013–1.107) | 0.011* | 1.082 (1.029–1.138) | 0.002 |
| Gender (male) | 0.508 (0.234–1.103) | 0.087* | ||
| BMI (per kg/m2) | 1.026 (0.911–1.154) | 0.674 | ||
| CEAa (per μg/L) | 1.012 (0.996–1.029) | 0.130 | ||
| ASA grade | ||||
| I | ||||
| II | 2.086 (0.795–5.473) | 2.086 | ||
| III | 1.378 (0.256–7.406) | 0.708 | ||
| Comorbidity | ||||
| Diabetes | 1.378 (0.256–7.406) | 0.708 | ||
| Chronic obstructive pulmonary disease | 1.089 (0.192–6.187) | 0.924 | ||
| Surgery | ||||
| Open resection (versus laparoscopic) | 6.390 (1.900–21.491) | 0.003* | 6.798 (1.082–24.580) | 0.003 |
| Major (versus minor) | 1.149 (0.549–2.402) | 0.712 | ||
| Resection + RFA (versus only resection) | 1.800 (0.658–4.920) | 0.252 | ||
| Blood loss (per ml) | 1.001 (1.000–1.001) | 0.127 | ||
| Operation time (per min) | 1.007 (1.00–1.015) | 0.041* | 1.009 (1.001–1.017) | 0.033 |
OR odds ratio, CI confidence interval, BMI body mass index, CEA carcinoembryonic antigen, ASA American Society of Anesthesiologists, RFA radiofrequency ablation
Bold variables were considered statistically significant (P < 0.05). *Variables that were taken into the multivariable analysis (P < 0.010)
a28 patients missing