Table 2.
Age-adjusted Spearman correlations of leukocyte telomere length and mitochondria DNA copy number with body shape/BMI/waist circumference across the lifespan among women in the Nurses’ Health Study
Body shape | Body shape | BMI | BMI | BMI | BMI | BMI change | Waist circumference | |
---|---|---|---|---|---|---|---|---|
(age 5) | (age 10) | (age 18) | (age 40) | (age 50) | (age 60) | (age 18–60) | (in 1986) | |
TL z-score | ||||||||
N | 7908 | 7949 | 7858 | 3441 | 7267 | 8135 | 7782 | 6011 |
rsa | 0.01 | 0.002 | 0.005 | −0.02 | −.02b | −.03c | −.03c | −.03c |
mtCN z-score | ||||||||
N | 3846 | 3868 | 3811 | 1734 | 3556 | 3952 | 3769 | 2885 |
rsa | −0.02 | −.04b | −.04b | −.07c | −.04b | −.05c | −0.03 | −.05c |
Spearman correlation coefficient adjusted for age at blood collection.
P < 0.05.
P < 0.01.
Abbreviations: BMI, body mass index; TL, telomere length; mtCN, mitochondrial DNA copy number.