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. Author manuscript; available in PMC: 2021 Apr 23.
Published in final edited form as: Immunol Cell Biol. 2017 Dec 19;96(2):212–228. doi: 10.1111/imcb.1032

Figure 4.

Figure 4.

NK cell stimulation with IL-2 and/or K562-mbIL21 triggers HLA-DR surface expression on HLA-DR-negative cells. (a) HLA-DR expression in HLA-DR+ and HLA-DR− NK cell subsets after 6 days of incubation with indicated stimuli. (b) Presence of HLA-DR α-subunit mRNA in NK cells, freshly isolated and after 6 days of stimulation (upper row), and in HLA-DR-positive and HLA-DR-negative NK cells directly after sorting in “Single cell” mode (bottom row). (a, b) Representative data obtained from a single donor out of three donors examined are shown. (c) Changes in HLA-DR expression in clones, obtained from freshly isolated unsorted NK cells. (d) Changes in HLA-DR expression in clones, obtained from freshly isolated HLA-DR-negative NK cells subset. Representative data obtained from a single clone out of 20 (c) or 24 (d) clones examined, respectively, are shown in each figure.