Table 2.
Functional domains and their tests for both study participant and study partner
| Functional domain | RMT | Paper pencil test |
|---|---|---|
| 1. Difficulties at work | AIADL (via email)1 | AIADL (in clinic)2 |
| 2. Spatial navigation and memory | Altoida MD1,2, pRMT1, AIADL (via email)1 | ECog2, AIADL (in clinic)2, ADCS-ADL2 |
| 3. Planning skills and memory required for task-completion | Altoida MD1,2, Mezurio1, AIADL (via email)1 | DSST2, E-Cog2, AIADL (in clinic)2, ADCS-ADL2, CERAD2 |
| 4. Managing finances | Banking app2, AIADL (via email)1 | ECog2, AIADL (in clinic)2, ADCS-ADL2, SFS2 |
| 5. Self-care | AIADL (via email)1, RAS1, Camera1 | AIADL (in clinic)2, ADCS-ADL2, SFS2 |
| 6. Self-management, e.g., running errands and shopping | Mezurio1, AIADL (via email)1, RAS1 | E-Cog2, AIADL2, ADCS-ADL2, SFS2, NPI2 |
| 7. Acquiring new skills | Mezurio1 | CERAD2 |
| 8. Sleep quality and circadian rhythms | Fitbit1, Axivity1, Mezurio1, DREEM1 | PSQI2, ESS2, NPI2 |
| 9. Use of technology/devices | Altoida MD1,2, pRMT1, Mezurio1, AIADL (via email)1 | ECog2, AIADL2, SFS2, Smartphone proficiency test2 |
| 10. Dysnomia, word-finding difficulties | Mezurio1 | CERAD2 |
| 11. Gait | Fitbit1, Axivity1, Gait Up2 | E-Cog2, ADCS-ADL2 |
| 12. Difficulties driving | CANEdge1, AIADL (via email)1 | E-Cog2, AIADL (in clinic)2 |
| 13. Interpersonal interaction | pRMT1, Camera1 | SFS2 |
| 14. Motivation, signs of apathy or withdrawal | pRMT1, Mezurio1, Camera1 | SFS2, NPI2 |
1Used in participant’s own environments
2In-clinic test
ADCS-ADL Alzheimer’s Disease Cooperative Study—Activities of Daily Living scale; AIADL Amsterdam Instrumented Activities of Daily Living; Altoida MD Altoida Medical Device; Axivity Axivity AX3 activity tracker; Camera Autographer wearable camera; CANEdge CANedge driving performance logger; CERAD CERAD neuropsychological test battery, consisting of verbal fluency (animal naming), 15-item Boston Naming Test, word list learning, word list recall, word list recognition, Rey Complex Figure drawing and recall; DREEM DREEM device; DSST Digit Symbol Substitution Test; Ecog Everyday cognition; ESS Epworth Sleepiness Scale; Fitbit Fitbit Charge 3 activity tracker; Gait Up Gait Up Physilog sensors; Mezurio Mezurio smartphone application; NPI Neuropsychiatric Inventory; pRMT RADAR passive RMT app; PSQI Pittsburgh Sleep Quality Inventory; RAS residential activity sensors; SFS Social Functioning Scale