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. 2021 Apr 9;11:584884. doi: 10.3389/fonc.2021.584884

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Copyright © 2021 Cheng, Wang, Qi, Liu, Wang, Wan, Liu, Su, Jin, Liu, Li, Sang, Yang, Liu, Duan and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of TME-related mRNAs. (A) Heatmap of DEmRNAs between high and low immune groups. (B) Heatmap of DEmRNAs between high and low stromal groups. (C) Volcano map of mRNAs expression between high and low immune groups. (D) Volcano map of mRNAs expression between high and low stromal groups. (E) Venn diagram was used for the intersection of DEmRNAs within immune and stromal groups, we considered the common DEmRNAs to be TME-related mRNAs. (F) GO enrichment analysis was performed to annotate TME-related DEmRNAs: the larger the bubble and longer columns represent the more genes enriched in this function, the deeper the color of the bubble and bars, the smaller the P value. (G) TME-related DEmRNAs KEGG enrichment analysis results.