Table 1.

Kinetic parameters (defined in Fig. 2) for the effects of compounds on ATP binding and isomerization in the actin–compound-S1 complex

Experimental conditions for stopped-flow experiments: F-Mg buffer, 25 °C. Values are mean ± SEM for four to seven replicates. ORIGIN fitting errors are reported for calculated equilibrium and rate constants. The effects for 1/K₁ and k₊₂ are categorized as mild (blue): <1.5-fold; moderate (violet): 1.5- to 3-fold; and severe (pink): >3-fold.