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. 2021 Mar 24;10(4):503. doi: 10.3390/antiox10040503

Table 1.

Analytic methods for serum albumin (ALB) redox state.

Method Strengths Weaknesses
HPLC Sperior to quantify ALB isoforms Cannot determine post-translational modifications
LC-MS Sperior to characterize post-translational modifications Less quantitative
Colorimetric Simple and rapid Less accurate and informative

HPLC, high-performance liquid chromatography; and LC-MS, liquid chromatography coupled with mass spectrometry.