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. 2021 Mar 24;10(4):254. doi: 10.3390/biology10040254

Figure 2.

Figure 2

Uninjured FMT donor rats displayed altered baseline levels of anxiety-like behaviour and proportions of fecal Lactobacillus. (A) Fecal microbiota transplant (FMT) donors travelled significantly less distance in the open field compared to the SCI + vehicle and SCI + FMT treatment groups in the present experiment (measured at baseline prior to SCI). (B) Fecal matter from FMT donors had significantly decreased baseline proportions of Lactobacillus, which is also reflected in the decreased amount of Lactobacillus found in the FMT solution. (C) All groups had similar baseline levels of alpha diversity, including the FMT solution. (D) FMT donors in the current study displayed significantly increased anxiety-like behaviour in the elevated plus maze (indicated by the percent of time spent in the open arms) and (E) had significantly less fecal proportion of Lactobacillus relative to successful FMT donor rats from previous experiments. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001. Gold star represents the FMT solution (A single value and therefore not included in statistical analysis). Error bars represent standard error mean.