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. 2021 Mar 24;10(4):254. doi: 10.3390/biology10040254

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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FMT from anxious donors did not prevent gut dysbiosis following SCI. (A) PCoA plot of beta diversity shows the diversity between fecal samples over time on the day of injury (DOI), 3-, 7-, 14- and 56-days post-injury (DPI). (B) The same PCoA plot is shown with the colors representing the groups instead of timepoints. Axis 1 and 2 explain 4.683% and 8.724% of the variance between samples, respectively. (C) There was no effect of injury or treatment on the alpha diversity. The four most abundant operational taxonomic units at the phylum level also show no differences between experimental groups in the proportion of (D) Bacteroidetes, (E) Firmicutes, (F) Proteobacteria and (G) Cyanobacteria. (H) The proportion of the genus Lactobacillus was reduced after SCI but not affected by FMT. Red lines represent baseline values. Error bars represent standard error mean.