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. 2021 Mar 24;10(4):254. doi: 10.3390/biology10040254

Figure 6.

Figure 6

FMT from anxious donors resulted in a chronic increase in anxiety-like behaviour after SCI. At the end of rehabilitative training, rats were tested for anxiety-like and depressive-like behaviours. (A) Schematic of a rat in the open arm of the elevated plus maze. (B) SCI + FMT rats spent significantly less time in the open arms compared to untreated rats. (C) Both groups of rats travelled a similar amount of distance in the elevated plus maze. (D) SCI + FMT rats spent less time in the light-component of the light-dark box and (E) drank less sucrose water than untreated rats (each data point represents a cage containing 5 rats, each of which were considered for statistical analyses). (F) Both fecal transplant treated and untreated rats spent a similar amount of time interacting in the social interaction test. * p < 0.05, **** p < 0.0001. Error bars represent standard error mean.