Table 2.
Early protection of pigs vaccinated with the A/SKR/Yeoncheon/2017 (A-1) experimental vaccine and challenged with homologous FMDV at 7 DPV.
| Injection | Animal No. | Maximum Clinical Score (DPC of the First Detection) a |
Maximum Amount of Viremia b (DPC of the First Detection) |
VN Antibody Titer (log10) at 0 DPC |
|---|---|---|---|---|
| Vaccine | 1 | 2 (7) | 2.7 ± 0.7 × 103 (4) | 1.2 |
| 2 | 2 (5) | 1.7 ± 1.0 × 101 (6) | 2.4 | |
| 3 | Neg c | Neg | 2.3 | |
| 4 | Neg | Neg | 2.4 | |
| PBS | 5 | 10 (3) | 1.8 ± 0.5 × 105 (2) | <0.9 |
| 6 | 10 (3) | 2.5 ± 0.4 × 105 (4) | <0.9 | |
| 7 | 10 (3) | 4.5 ± 0.02 × 104 (2) | <0.9 |
a Data (copy number of FMDV/mL) represent the mean ± SD from triplicate RT-qPCR measurements. b DPC: days post challenge. c Neg: no viral RNA and no clinical signs were detected.