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. 2021 Mar 24;13(4):438. doi: 10.3390/pharmaceutics13040438

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Design and characterization of two amphipathic Antimicrobial peptides (AMPs). (A) Chemical structures of two active AMPs (WW304 and WW307). (B) Helical wheel projections of WW304 and WW307. The hydrophilic residues as circles, hydrophobic residues as diamonds, and potentially positively charged as pentagons. Hydrophobicity is color coded as well: the most hydrophobic residue is green, and the amount of green is decreasing proportionally to the hydrophobicity, with zero hydrophobicity coded as yellow.