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. 2021 Mar 24;13(4):437. doi: 10.3390/pharmaceutics13040437

Table 4.

Correlation coefficients (R2) and release exponent (n) values obtained from the different kinetic models for SLNs (upper) and NLCs (down) formulations.

Kinetic Model SLN1L SLN2L SLN4L SLN10L
Zero order 0.9239 0.8713 0.8578 0.9236
First order 0.927 0.8989 0.8995 0.9483
Higuchi 0.964 0.9313 0.9214 0.9690
Kormeyer-Peppas 0.9842 0.9538 0.9509 0.9862
Kormeyer-Peppas (n) 0.08 0.28 0.24 0.22
Kinetic model NLC1L NLC5L NLC9L NLC13L NLC14L
Zero order 0.9771 0.9527 0.9675 0.9639 0.9853
First order 0.9797 0.9756 0.9881 0.9751 0.9897
Higuchi 0.9955 0.9866 0.9940 0.9913 0.9992
Kormeyer-Peppas 0.9958 0.9939 0.9963 0.9933 0.9994
Kormeyer-Peppas (n) 0.13 0.33 0.40 0.39 0.42