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. Author manuscript; available in PMC: 2022 Mar 11.
Published in final edited form as: J Med Chem. 2021 Feb 12;64(5):2691–2704. doi: 10.1021/acs.jmedchem.0c01922

Figure 9:

Figure 9:

ROS generation in MV4–11 following incubation with 10 μM TO-317 for up to 4 h. TO-317 shows markedly increased levels of ROS after 2 h incubation which continues to increase up to the 4 h incubation time tested. Data reported is an average of duplicate studies.