Table 1.
Comparison of the value of the RM0 parameter for the investigated drugs with the use of different stationary phases in the methanol/water and acetone/water system.
| Compound | RP-18 | RP-8 | RP-2 | CN | DIOL | NH2 |
|---|---|---|---|---|---|---|
| methanol/water | ||||||
| P | 1.7048 | 2.1593 | 0.4712 | 1.0852 | 0.1564 | −0.1828 |
| M | 1.4589 | 1.8891 | 0.4114 | 0.6562 | 0.0194 | −0.1844 |
| T | 1.1124 | 1.9067 | 0.2685 | 0.8520 | 0.3358 | −0.2693 |
| I | 1.1091 | 1.7309 | 0.2371 | 0.7763 | 0.1040 | −0.1833 |
| C | 4.4357 | 3.5729 | 2.6661 | 3.1469 | 0.0391 | 1.0244 |
| E | 3.9062 | 3.2291 | 1.8448 | 2.3315 | 1.3283 | −0.2205 |
| R | 3.2075 | 2.2447 | 1.7526 | 1.5973 | -0.0476 | −0.1692 |
| V | 3.5034 | 2.6716 | 2.2324 | 2.4693 | 0.0301 | −0.2128 |
| CI | 2.9465 | 2.8658 | 2.3930 | 2.6595 | 0.2266 | −0.0704 |
| F | 3.1951 | 3.6857 | 2.3601 | 2.3322 | 0.2161 | −0.2016 |
| RB | 3.5298 | 2.6288 | 1.1382 | 1.7518 | 0.4835 | 0.3421 |
| acetone/water | ||||||
| P | 0.7572 | 1.3335 | −0.0885 | 0.7418 | 0.1111 | −0.6842 |
| M | 0.6441 | 1.1021 | 0.0757 | 0.7942 | −0.3837 | −0.5738 |
| T | 0.3949 | 0.8081 | −0.1169 | 0.5707 | −0.2370 | −0.6496 |
| I | 0.4835 | 0.9569 | −0.2855 | 0.7894 | 0.7019 | −0.7145 |
| C | 3.7555 | 3.2575 | 2.3937 | 2.4404 | 0.3972 | 1.4811 |
| E | 2.5362 | 2.3901 | 1.7092 | 1.8886 | 0.9818 | −0.5460 |
| R | 2.2732 | 2.0335 | 1.8214 | 1.5941 | −0.0734 | −0.3690 |
| V | 2.6983 | 2.3689 | 2.1503 | 1.8632 | −0.0599 | 0.1163 |
| CI | 3.0736 | 3.0720 | 2.1178 | 1.9163 | −0.1515 | −0.6185 |
| F | 2.5679 | 2.7347 | 2.4046 | 1.9880 | −0.4958 | −0.6517 |
| RB | 2.8466 | 2.1131 | 2.9562 | 1.5364 | 0.0210 | 0.8523 |