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. 2021 Mar 24;10(4):724. doi: 10.3390/cells10040724

Figure 5.

Figure 5

Influence of CB1R inhibitor O2050 on the effects of angiotensin II (Ang II) on coronary flow (A), left ventricular developed pressure (LVDevP) (B), +dLVP/dtmax (C) and −dLVP/dtmax (D) of isolated rat hearts. Ang II (10−7 M) was administered repetitively to the perfusate. The presented data were recorded during the second infusion period, when Ang II was infused either in the presence of CB1R inhibitor O2050 (10−6 M) or its vehicle and are expressed as relative values compared to pre-infusion control data. Mean ± SEM; n = 7 & 8; * p < 0.05 vs. control (pre-infusion value); ### p < 0.001 vs. vehicle; two-way repeated measurement ANOVA and Dunnett’s post-hoc test.