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. 2021 Apr 7;13(7):9455–9467. doi: 10.18632/aging.202930

Table 3. Cohort baseline characteristics.

Cohort Total ASPS ASPS-Fam p*
N 390 242 148
females, N (%) 241 (61.8%) 151 (62.4%) 90 (60.8%) 0.75
age (years), median [IQR] 69 [63-74] 69 [64 - 75] 68 [55 - 75] 0.002
education (years), median [IQR] 10 [9-13] 10 [9 - 10] 10 [10 - 13] 0.001
hypertension, N (%) 286 (73.3%) 187 (77.3%) 99 (66.9%) 0.24
diabetes, N (%) 49 (12.6%) 31 (12.8%) 18 (12.2%) 0.85
atrial fibrillation, N (%) 23 (5.9%) 14 (5.8%) 9 (6.1%) 0.90
25(OH)D3 (nmol/L), median [IQR] 58.8 [39.5 – 76.0] 58.4 [37.9 - 77.9] 59.5 [42.8 - 72.8] 0.76
25(OH)D2 (nmol/L), median [IQR] 1.6 [1.0 – 2.5] 1.4 [0.9 - 1.9] 2.2 [1.3 - 3.3] 9.6 x 10-10
total 25(OH)D (nmol/L), median [IQR] 60.4 [42.2 – 78.5] 59.7 [40.0 – 79.8] 61.4 [46.1 – 75.2] 0.56
24,25(OH)2D3 (nmol/L), median [IQR] 3.1 [1.6 – 4.6] 3.1 [1.5 – 4.8] 3.2 [1.9 - 4.5] 0.77
VMR (%), median [IQR] 5.2 [3.9 – 6.8] 5.1 [3.7 - 6.8] 5.4 [4.0 - 6.9] 0.43
blood samples: spring, N (%) 118 (30.3%) 51 (21.2%) 67 (45.3%)
blood samples: summer, N (%) 110 (28.2%) 76 (31.4%) 34 (23.0%)
blood samples: autumn, N (%) 87 (22.3%) 66 (28.3%) 21 (14.2%)
blood samples: winter, N (%) 75 (19.2%) 49 (20.2%) 26 (17.6%)

ASPS: Austrian Stroke Prevention Study; ASPS-Fam: Austrian Stroke Prevention Family Study; VMR: vitamin D metabolite ratio. *Chi-Square test was used to compare categorical variables and Mann-Whitney-U test was used to compare the non-normally distributed continuous variables between ASPS and ASPS-Fam.