Table 1. Mortality risks by intensity of TILs for overall survival and disease-free survival.

Group	TILs intensity	Overall survival				Disease-free survival
		No. of cases/total	Adjusted HR a	P		No. of cases/total	Adjusted HR a	P
Discovery phase (WCH set)
Low	TILs < 10%	67/172	1 (reference)			80/103	1 (reference)
Intermediate	10% ≦ TILs <50%	24/106	0.58 (0.36-0.93)	0.02		21/58	0.35 (0.22-0.58)	4.59 × 10-5
High	TILs ≧ 50%	5/34	0.37 (0.15-0.93)	0.04		5/22	0.23 (0.09-0.58)	1.83 × 10-3
P for trend				4.25 × 10-3				3.60 × 10-6
Validation phase (TCGA set)
Low	TILs < 10%	81/181	1 (reference)			100/154	1 (reference)
Intermediate	10% ≦ TILs <50%	30/123	0.42 (0.28-0.66)	1.13 × 10-4		50/111	0.52(0.37-0.74)	2.78 × 10-4
High	TILs ≧ 50%	8/39	0.41 (0.19-0.86)	0.02		11/33	0.33 (0.17-0.62)	6.09 × 10-4
P for trend				1.08 × 10-4				8.25 × 10-6

^aAdjusted for age, sex, tumor stage and tumor grade.