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. 2021 Mar 26;13(7):10225–10239. doi: 10.18632/aging.202782

Table 1. Patient characteristics.

Total AITL PTCL, NOS NK/TCL ALK+ALCL ALK-ALCL Others
Overall 650 91 65 280 55 33 126
Sex
Male 455 (70.0%) 57 (62.6%) 49 (75.4%) 205 (73.2%) 41 (74.5%) 24 (72.7%) 82 (65.1%)
Female 195 (30.0 %) 34 (37.4%) 16 (24.6%) 75 (26.8%) 14 (25.5%) 9 (27.3%) 44 (34.9%)
Age (yr)
< 60 502 (77.2%) 44 (48.4%) 49 (75.4%) 242 (86.4%) 52 (94.5%) 17 (51.5%) 98 (77.8%)
≥ 60 148 (22.8%) 47 (51.6%) 16 (24.6%) 38 (13.6%) 3 (5.5%) 16 (48.5%) 28 (22.2%)
Stage
I-II 245 (37.7%) 1 (1.1%) 10 (15.4%) 163 (58.2%) 18 (32.7%) 20 (60.6%) 33 (26.2%)
III-IV 405 (62.3%) 90 (98.9%) 55 (84.6%) 117 (41.8%) 37 (67.3%) 13 (39.4%) 93 (73.8%)
LDH*
< ULN 402 (61.8%) 38 (41.8%) 36 (55.4%) 194 (69.3%) 32 (58.2%) 22 (66.7%) 80 (63.5%)
≥ ULN 248 (38.2%) 53 (58.2%) 29 (44.6%) 86 (30.7%) 23 (41.8%) 11 (33.3%) 46 (36.5%)
Extranodal sites
< 2 437 (67.2%) 73 (80.2%) 45 (69.2%) 161 (57.5%) 41 (74.5%) 26 (78.8%) 91 (72.2%)
≥ 2 213 (32.8%) 18 (19.8%) 20 (30.8%) 119 (42.5%) 14 (25.5%) 7 (21.2%) 35 (27.8%)
ECOG
< 2 584 (89.8%) 74 (81.3%) 59 (90.8%) 257 (91.8%) 49 (89.1%) 32 (97/0%) 113 (89.7%)
≥ 2 66 (10.2%) 17 (18.7%) 6 (9.2%) 23 (8.2%) 6 (10.9%) 1 (3.0%) 13 (10.3%)
Risk groups
Low 303 (46.6%) 19 (20.9%) 21 (32.3%) 154 (55%) 31 (56.4%) 19 (57.6%) 59 (46.8%)
Low-intermediate 192 (29.5%) 28 (30.8%) 23 (35.4%) 76 (27.1%) 16 (29.1%) 7 (21.2%) 42 (33.3%)
High-intermediate 111 (17.1%) 29 (31.9%) 17 (26.2%) 37 (13.2%) 5 (9.1%) 5 (15.2%) 18 (14.3%)
High 44 (6.8%) 15 (16.5%) 4 (6.2%) 13 (4.6%) 3 (5.5%) 2 (6.1%) 7 (5.6%)

AITL: angioimmunoblastic T-cell lymphoma; ALK: anaplastic lymphoma kinase positive; ALCL: anaplastic large cell lymphoma; PTCL: peripheral T-cell lymphoma; NKTCL: NK/T cell lymphoma. PTCL, NOS: peripheral T-cell lymphoma, unspecified. LDH: lactate dehydrogenase; ULN: upper limit of normal; ECOG: Eastern Cooperative Oncology Group.

*The upper limit of normal for LDH was defined as 240 IU/L.