Table 1. Patient characteristics.
Total | AITL | PTCL, NOS | NK/TCL | ALK+ALCL | ALK-ALCL | Others | |
Overall | 650 | 91 | 65 | 280 | 55 | 33 | 126 |
Sex | |||||||
Male | 455 (70.0%) | 57 (62.6%) | 49 (75.4%) | 205 (73.2%) | 41 (74.5%) | 24 (72.7%) | 82 (65.1%) |
Female | 195 (30.0 %) | 34 (37.4%) | 16 (24.6%) | 75 (26.8%) | 14 (25.5%) | 9 (27.3%) | 44 (34.9%) |
Age (yr) | |||||||
< 60 | 502 (77.2%) | 44 (48.4%) | 49 (75.4%) | 242 (86.4%) | 52 (94.5%) | 17 (51.5%) | 98 (77.8%) |
≥ 60 | 148 (22.8%) | 47 (51.6%) | 16 (24.6%) | 38 (13.6%) | 3 (5.5%) | 16 (48.5%) | 28 (22.2%) |
Stage | |||||||
I-II | 245 (37.7%) | 1 (1.1%) | 10 (15.4%) | 163 (58.2%) | 18 (32.7%) | 20 (60.6%) | 33 (26.2%) |
III-IV | 405 (62.3%) | 90 (98.9%) | 55 (84.6%) | 117 (41.8%) | 37 (67.3%) | 13 (39.4%) | 93 (73.8%) |
LDH* | |||||||
< ULN | 402 (61.8%) | 38 (41.8%) | 36 (55.4%) | 194 (69.3%) | 32 (58.2%) | 22 (66.7%) | 80 (63.5%) |
≥ ULN | 248 (38.2%) | 53 (58.2%) | 29 (44.6%) | 86 (30.7%) | 23 (41.8%) | 11 (33.3%) | 46 (36.5%) |
Extranodal sites | |||||||
< 2 | 437 (67.2%) | 73 (80.2%) | 45 (69.2%) | 161 (57.5%) | 41 (74.5%) | 26 (78.8%) | 91 (72.2%) |
≥ 2 | 213 (32.8%) | 18 (19.8%) | 20 (30.8%) | 119 (42.5%) | 14 (25.5%) | 7 (21.2%) | 35 (27.8%) |
ECOG | |||||||
< 2 | 584 (89.8%) | 74 (81.3%) | 59 (90.8%) | 257 (91.8%) | 49 (89.1%) | 32 (97/0%) | 113 (89.7%) |
≥ 2 | 66 (10.2%) | 17 (18.7%) | 6 (9.2%) | 23 (8.2%) | 6 (10.9%) | 1 (3.0%) | 13 (10.3%) |
Risk groups | |||||||
Low | 303 (46.6%) | 19 (20.9%) | 21 (32.3%) | 154 (55%) | 31 (56.4%) | 19 (57.6%) | 59 (46.8%) |
Low-intermediate | 192 (29.5%) | 28 (30.8%) | 23 (35.4%) | 76 (27.1%) | 16 (29.1%) | 7 (21.2%) | 42 (33.3%) |
High-intermediate | 111 (17.1%) | 29 (31.9%) | 17 (26.2%) | 37 (13.2%) | 5 (9.1%) | 5 (15.2%) | 18 (14.3%) |
High | 44 (6.8%) | 15 (16.5%) | 4 (6.2%) | 13 (4.6%) | 3 (5.5%) | 2 (6.1%) | 7 (5.6%) |
AITL: angioimmunoblastic T-cell lymphoma; ALK: anaplastic lymphoma kinase positive; ALCL: anaplastic large cell lymphoma; PTCL: peripheral T-cell lymphoma; NKTCL: NK/T cell lymphoma. PTCL, NOS: peripheral T-cell lymphoma, unspecified. LDH: lactate dehydrogenase; ULN: upper limit of normal; ECOG: Eastern Cooperative Oncology Group.
*The upper limit of normal for LDH was defined as 240 IU/L.