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. 2021 Apr 4;13(7):10468–10489. doi: 10.18632/aging.202809

Table 1. The number cases, age-standardized rates, and EAPCs in incidence and prevalence for leukemia.

Incidence Prevalence
Number, 2017
(95% UI)
ASR/100,000,
2017 (95% UI)
EAPC(%) 1990 to 2017 (95% CI) P Number, 2017
(95% UI)
ASR/100,000,
2017 (95% UI)
EAPC(%), 1990 to 2017 (95% CI) P
Global 518485
(472240 to 548018)
6.76
(6.15 to 7.16)
-0.42
(-0.48 to -0.38)
<0.01 2432388
(2190332 to 2591602)
32.36
(29.02 to 34.61)
0.22
(0.13 to 0.31)
<0.01
Sex
Male 295386
(262628 to 314881)
8.09
(7.25 to 8.62)
-0.26
(-0.32 to -0.21)
<0.01 1337374
(1178388 to 1440142)
36.33
(32.14 to 39.18)
0.43
(0.34 to 0.53)
<0.01
Female 223099
(193548 to 239786)
5.62
(4.85 to 6.07)
-0.65
(-0.70 to -0.60)
<0.01 1095013
(941509 to 1202828)
28.75
(24.65 to 31.83)
-0.03
(-0.12 to 0.06)
0.446
Social-demographic index
Low SDI 42637(36388 to 47928) 4.14(3.51 to 4.62) -0.55(-0.60 to -0.50) <0.01 145711(122494 to 166885) 12.68(10.66 to 14.32) -0.82(-0.86 to -0.77) <0.01
Low-middle SDI 66803(60348 to 76400) 4.54(4.11 to 5.21) -0.34(-0.40 to -0.28) <0.01 238763(212407 to 275094) 15.33(13.68 to 17.69) -0.62(-0.68 to -0.57) <0.01
Middle SDI 131867
(115140 to 709328)
6.47
(5.68 to 6.98)
-0.19
(-0.34 to -0.04)
0.014 644896
(561580 to 709328)
33.31
(29.06 to 37.16)
0.61
(0.33 to 0.90)
<0.01
High-middle SDI 123669
(106214 to 132373)
8.68
(7.43 to 9.46)
0.56
(0.50 to 0.63)
<0.01 716765
(599293 to 785871)
59.02
(47.60 to 66.39)
2.52
(2.37 to 2.66)
<0.01
High SDI 150825
(145068 to 156387)
7.73
(7.43 to 8.02)
-0.67
(-0.74 to -0.60)
<0.01 669515
(643865 to 693443)
44.21
(41.80 to 46.21)
0.02
(-0.09 to 0.14)
0.666
Region
Central Asia 4027(3676 to 4408) 4.74(4.36 to 5.16) -0.20(-0.31 to -0.08) <0.01 17276 (14860 to 20638) 19.74(17.14 to 23.32) 0.04(-0.05 to 0.14) 0.371
Central Europe 11075(10405 to 11569) 6.37(5.95 to 6.72) 0.03(-0.12 to 0.17) 0.732 50380 (47177 to 53093) 35.22(31.85 to 38.95) 1.28(1.12 to 1.44) <0.01
Eastern Europe 19717(18142 to 21322) 6.91(6.35 to 7.55) 0.06 (-0.08 to 0.21) 0.361 93861 (84126 to 104508) 37.52(31.97 to 43.78) 1.02(0.71 to 1.33) <0.01
Australasia 4208(3602 to 4871) 9.62(8.33 to 11.02) -1.65(-1.92 to -1.38) <0.01 21638 (18625 to 25187) 60.56(51.70 to 70.58) -0.96(-1.36 to -0.56) <0.01
High-income Asia Pacific 17764(16084 to 19509) 5.27(4.80 to 5.81) -0.47(-0.57 to -0.38) <0.01 64160 (58413 to 70356) 30.54(26.64 to 35.38) 0.57(0.40 to 0.73) <0.01
High-income North America 39552(38013 to 41478) 7.17(6.89 to 7.57) -0.61(-0.78 to -0.43) <0.01 184297(176809 to 194962) 36.74(35.07 to 38.98) -0.41(-0.64 to -0.18) <0.01
Southern Latin America 3932(3626 to 4260) 5.29(4.88 to 5.76) -0.68(-0.75 to-0.61) <0.01 14466 (12992 to 16559) 20.88(18.34 to 24.89) -0.05(-0.12 to -0.02) 0.186
Western Europe 75694(71159 to 80241) 8.86(8.36 to 9.35) -0.76(-0.83 to -0.69) <0.01 323056(305276 to 341225) 49.93(46.86 to 53.40) -0.29(-0.44 to -0.13) <0.01
Andean Latin America 3531(2892 to 4023) 5.97(4.93 to 6.77) 0.76(-0.09 to 1.65) 0.076 13987 (11127 to 16935) 23.12(18.60 to 27.76) -0.01(-0.16 to 0.14) 0.899
Caribbean 2797(2538 to 3200) 5.82(5.25 to 6.71) -0.59(-0.68 to -0.50) <0.01 10806 (9573 to 12678) 23.15(20.30 to 27.56) -0.35(-0.44 to -0.26) <0.01
Central Latin America 14489(13845 to 15395) 5.89(5.63 to 6.24) -0.32(-0.38 to -0.27) <0.01 58671 (54683 to 63720) 23.93(22.28 to 26.05) 0.10(0.06 to 0.14) <0.01
Tropical Latin America 10170(9861 to 10602) 4.65(4.48 to 4.86) -0.58(-0.67 to -0.49) <0.01 34480 (32765 to 37233) 16.50(15.49 to 18.02) -0.33(-0.41 to -0.25) <0.01
North Africa and Middle East 32334(28685 to 36500) 6.37(5.63 to 7.19) -0.24(-0.31 to -0.17) <0.01 140390(124045 to 164467) 26.15(23.30 to 30.33) 0.41(0.31 to 0.50) <0.01
South Asia 62007(53796 to 69680) 3.99(3.46 to 4.47) -0.30(-0.39 to -0.22) <0.01 189850(162175 to 214710) 11.71(10.02 to 13.23) -0.68(-0.77 to -0.60) <0.01
East Asia 147726
(124458 to 161336)
10.54
(8.81 to 11.71)
0.83
(0.63 to 1.02)
<0.01 964845
(801062 to 1067449)
81.97
(66.17 to 93.10)
2.95
(2.64 to3.26)
<0.01
Oceania 623(483 to 802) 6.34(4.99 to 7.65) -0.07(-0.11 to -0.03) <0.01 2156 (1610 to 2921) 20.16(15.69 to 25.41) -0.02(-0.08 to -0.03) 0.341
Southeast Asia 38894(32374 to 42316) 3.99(3.46 to 4.47) 0.07(-0.04 to 0.19) 0.182 141696(116203 to 155338) 11.71(10.02 to 13.23) -0.08(-0.02 to 0,02) 0.143
Central Sub-Saharan Africa 3402(2400 to 4400) 3.87(2.90 to 4.60) -0.24(-0.27 to -0.20) <0.01 12447 (7939 to 18702) 11.76(8.41 to 12.41) -0.43(-0.48 to -0.38) <0.01
Eastern Sub-Saharan Africa 13301(10190 to 16009) 4.48(3.52 to 5.21) -0.29(-0.38 to -0.20) <0.01 49051 (36380 to 61198) 14.17(10.82 to 16.83) -0.31(-0.41 to -0.21) <0.01
Southern Sub-Saharan Africa 2491(2014 to 2709) 4.10(3.35 to 4.44) -0.31(-0.69 to -0.08) 0.117 7645 (6095 to 8688) 12.21(9.83 to 13.68) -0.45(-0.80 to -0.08) 0.017
Western Sub-Saharan Africa 10753(8701 to 12661) 3.40(2.76 to 4.01) -0.14(-0.23 to -0.05) <0.01 37230 (29402 to 44826) 10.78(8.75 to 12.91) -0.30(-0.42 to -0.17) <0.01