Table 1. The number cases, age-standardized rates, and EAPCs in incidence and prevalence for leukemia.
Incidence | Prevalence | ||||||||
Number, 2017 (95% UI) |
ASR/100,000, 2017 (95% UI) |
EAPC(%) 1990 to 2017 (95% CI) | P |
Number, 2017 (95% UI) |
ASR/100,000, 2017 (95% UI) |
EAPC(%), 1990 to 2017 (95% CI) | P | ||
Global | 518485 (472240 to 548018) |
6.76 (6.15 to 7.16) |
-0.42 (-0.48 to -0.38) |
<0.01 | 2432388 (2190332 to 2591602) |
32.36 (29.02 to 34.61) |
0.22 (0.13 to 0.31) |
<0.01 | |
Sex | |||||||||
Male | 295386 (262628 to 314881) |
8.09 (7.25 to 8.62) |
-0.26 (-0.32 to -0.21) |
<0.01 | 1337374 (1178388 to 1440142) |
36.33 (32.14 to 39.18) |
0.43 (0.34 to 0.53) |
<0.01 | |
Female | 223099 (193548 to 239786) |
5.62 (4.85 to 6.07) |
-0.65 (-0.70 to -0.60) |
<0.01 | 1095013 (941509 to 1202828) |
28.75 (24.65 to 31.83) |
-0.03 (-0.12 to 0.06) |
0.446 | |
Social-demographic index | |||||||||
Low SDI | 42637(36388 to 47928) | 4.14(3.51 to 4.62) | -0.55(-0.60 to -0.50) | <0.01 | 145711(122494 to 166885) | 12.68(10.66 to 14.32) | -0.82(-0.86 to -0.77) | <0.01 | |
Low-middle SDI | 66803(60348 to 76400) | 4.54(4.11 to 5.21) | -0.34(-0.40 to -0.28) | <0.01 | 238763(212407 to 275094) | 15.33(13.68 to 17.69) | -0.62(-0.68 to -0.57) | <0.01 | |
Middle SDI | 131867 (115140 to 709328) |
6.47 (5.68 to 6.98) |
-0.19 (-0.34 to -0.04) |
0.014 | 644896 (561580 to 709328) |
33.31 (29.06 to 37.16) |
0.61 (0.33 to 0.90) |
<0.01 | |
High-middle SDI | 123669 (106214 to 132373) |
8.68 (7.43 to 9.46) |
0.56 (0.50 to 0.63) |
<0.01 | 716765 (599293 to 785871) |
59.02 (47.60 to 66.39) |
2.52 (2.37 to 2.66) |
<0.01 | |
High SDI | 150825 (145068 to 156387) |
7.73 (7.43 to 8.02) |
-0.67 (-0.74 to -0.60) |
<0.01 | 669515 (643865 to 693443) |
44.21 (41.80 to 46.21) |
0.02 (-0.09 to 0.14) |
0.666 | |
Region | |||||||||
Central Asia | 4027(3676 to 4408) | 4.74(4.36 to 5.16) | -0.20(-0.31 to -0.08) | <0.01 | 17276 (14860 to 20638) | 19.74(17.14 to 23.32) | 0.04(-0.05 to 0.14) | 0.371 | |
Central Europe | 11075(10405 to 11569) | 6.37(5.95 to 6.72) | 0.03(-0.12 to 0.17) | 0.732 | 50380 (47177 to 53093) | 35.22(31.85 to 38.95) | 1.28(1.12 to 1.44) | <0.01 | |
Eastern Europe | 19717(18142 to 21322) | 6.91(6.35 to 7.55) | 0.06 (-0.08 to 0.21) | 0.361 | 93861 (84126 to 104508) | 37.52(31.97 to 43.78) | 1.02(0.71 to 1.33) | <0.01 | |
Australasia | 4208(3602 to 4871) | 9.62(8.33 to 11.02) | -1.65(-1.92 to -1.38) | <0.01 | 21638 (18625 to 25187) | 60.56(51.70 to 70.58) | -0.96(-1.36 to -0.56) | <0.01 | |
High-income Asia Pacific | 17764(16084 to 19509) | 5.27(4.80 to 5.81) | -0.47(-0.57 to -0.38) | <0.01 | 64160 (58413 to 70356) | 30.54(26.64 to 35.38) | 0.57(0.40 to 0.73) | <0.01 | |
High-income North America | 39552(38013 to 41478) | 7.17(6.89 to 7.57) | -0.61(-0.78 to -0.43) | <0.01 | 184297(176809 to 194962) | 36.74(35.07 to 38.98) | -0.41(-0.64 to -0.18) | <0.01 | |
Southern Latin America | 3932(3626 to 4260) | 5.29(4.88 to 5.76) | -0.68(-0.75 to-0.61) | <0.01 | 14466 (12992 to 16559) | 20.88(18.34 to 24.89) | -0.05(-0.12 to -0.02) | 0.186 | |
Western Europe | 75694(71159 to 80241) | 8.86(8.36 to 9.35) | -0.76(-0.83 to -0.69) | <0.01 | 323056(305276 to 341225) | 49.93(46.86 to 53.40) | -0.29(-0.44 to -0.13) | <0.01 | |
Andean Latin America | 3531(2892 to 4023) | 5.97(4.93 to 6.77) | 0.76(-0.09 to 1.65) | 0.076 | 13987 (11127 to 16935) | 23.12(18.60 to 27.76) | -0.01(-0.16 to 0.14) | 0.899 | |
Caribbean | 2797(2538 to 3200) | 5.82(5.25 to 6.71) | -0.59(-0.68 to -0.50) | <0.01 | 10806 (9573 to 12678) | 23.15(20.30 to 27.56) | -0.35(-0.44 to -0.26) | <0.01 | |
Central Latin America | 14489(13845 to 15395) | 5.89(5.63 to 6.24) | -0.32(-0.38 to -0.27) | <0.01 | 58671 (54683 to 63720) | 23.93(22.28 to 26.05) | 0.10(0.06 to 0.14) | <0.01 | |
Tropical Latin America | 10170(9861 to 10602) | 4.65(4.48 to 4.86) | -0.58(-0.67 to -0.49) | <0.01 | 34480 (32765 to 37233) | 16.50(15.49 to 18.02) | -0.33(-0.41 to -0.25) | <0.01 | |
North Africa and Middle East | 32334(28685 to 36500) | 6.37(5.63 to 7.19) | -0.24(-0.31 to -0.17) | <0.01 | 140390(124045 to 164467) | 26.15(23.30 to 30.33) | 0.41(0.31 to 0.50) | <0.01 | |
South Asia | 62007(53796 to 69680) | 3.99(3.46 to 4.47) | -0.30(-0.39 to -0.22) | <0.01 | 189850(162175 to 214710) | 11.71(10.02 to 13.23) | -0.68(-0.77 to -0.60) | <0.01 | |
East Asia | 147726 (124458 to 161336) |
10.54 (8.81 to 11.71) |
0.83 (0.63 to 1.02) |
<0.01 | 964845 (801062 to 1067449) |
81.97 (66.17 to 93.10) |
2.95 (2.64 to3.26) |
<0.01 | |
Oceania | 623(483 to 802) | 6.34(4.99 to 7.65) | -0.07(-0.11 to -0.03) | <0.01 | 2156 (1610 to 2921) | 20.16(15.69 to 25.41) | -0.02(-0.08 to -0.03) | 0.341 | |
Southeast Asia | 38894(32374 to 42316) | 3.99(3.46 to 4.47) | 0.07(-0.04 to 0.19) | 0.182 | 141696(116203 to 155338) | 11.71(10.02 to 13.23) | -0.08(-0.02 to 0,02) | 0.143 | |
Central Sub-Saharan Africa | 3402(2400 to 4400) | 3.87(2.90 to 4.60) | -0.24(-0.27 to -0.20) | <0.01 | 12447 (7939 to 18702) | 11.76(8.41 to 12.41) | -0.43(-0.48 to -0.38) | <0.01 | |
Eastern Sub-Saharan Africa | 13301(10190 to 16009) | 4.48(3.52 to 5.21) | -0.29(-0.38 to -0.20) | <0.01 | 49051 (36380 to 61198) | 14.17(10.82 to 16.83) | -0.31(-0.41 to -0.21) | <0.01 | |
Southern Sub-Saharan Africa | 2491(2014 to 2709) | 4.10(3.35 to 4.44) | -0.31(-0.69 to -0.08) | 0.117 | 7645 (6095 to 8688) | 12.21(9.83 to 13.68) | -0.45(-0.80 to -0.08) | 0.017 | |
Western Sub-Saharan Africa | 10753(8701 to 12661) | 3.40(2.76 to 4.01) | -0.14(-0.23 to -0.05) | <0.01 | 37230 (29402 to 44826) | 10.78(8.75 to 12.91) | -0.30(-0.42 to -0.17) | <0.01 |