. 2021 Feb 1;13(7):9510–9521. doi: 10.18632/aging.202438

Table 5. Regression analysis to identify associations between multidomain cognitive functions and total SVD score.

Domain		Linear regression analysis	Multivariable regression analysis
Domain		Linear regression analysis	Model 1^a	Model 2^b
overall cognition	B (95%CI)	-0.185 (-0.303, -0.068)	-0.190 (-0.313, -0.067)	-0.190 (-0.315, -0.064)
	P	0.002*	0.003*	0.003*
executive	B (95%CI)	-0.249 (-0.406, -0.092)	-0.268 (-0.429, -0.107)	-0.272 (-0.435, -0.109)
	P	0.002*	0.001**	0.001**
memory	B (95%CI)	-0.084 (-0.217, 0.049)	-0.118 (-0.254, 0.018)	-0.122 (-0.260, 0.016)
	P	0.214	0.088	0.084
language	B (95%CI)	-0.093 (-0.278, 0.092)	-0.077 (-0.260, 0.106)	-0.074 (-0.259, 0.110)
	P	0.323	0.406	0.427
visuospatial	B (95%CI)	-0.315 (-0.516, -0.114)	-0.296 (-0.506, -0.086)	-0.290 (-0.504, -0.075)
	P	0.002*	0.006*	0.009*

^aAdjusted for age, sex and educational level. ^bAdjusted for age, sex, educational level and vascular risk factors (hypertension, hypercholesterolemia, diabetes, smoking and drinking). *P<0.05. **P<0.001 Abbreviations: B, nonstandardized coefficients; CI, confidence interval.