Table 2. List of DEGs that met threshold criteria.
| Gene name | Gene descriptions | HGNC accession number | Log2FoldChange (females vs. males) D0/D03/D28/D180 | Chromosome | Gene strand |
| ALAS2 | 5'-aminolevulinate synthase 2 | 397 | 2.19/2.19/2.11/1.07 | X | - |
| FBXO7 | F-box protein 7 | 13586 | 1.11/1.02/1.03/0.77 | 22 | + |
| AHSP | alpha hemoglobin stabilizing protein | 18075 | 1.49/1.49/1.25/-0.76 | 16 | + |
| SLC4A1 | solute carrier family 4 member 1 (Diego blood group) | 11027 | 1.81/1.71/1.58/1.15 | 17 | - |
| TRIM58 | tripartite motif containing 58 | 24150 | 1.70/1.43 /1.45/1.61 | 1 | + |
| HBD | hemoglobin subunit delta | 4829 | 2.44/1.94/2.16/0.14 | 11 | - |
| RPS4Y1 | ribosomal protein S4 Y-linked 1 | 10425 | 0 | Y | + |
| SNCA | synuclein alpha | 11138 | 1.61/1.34/1.49/1.24 | 4 | - |
| MXI1 | MAX interactor 1, dimerization protein | 7534 | 1.25/1.02/1.11/1.18 | 10 | + |
| GSPT1 | G1 to S phase transition 1 | 4621 | 1.19/1.14/1.04/1.09 | 16 | - |
| HSPB1 | heat shock protein family B (small) member 1 | 5246 | 0.82/1.18/0.90/0.14 | 7 | + |
| SMOX | spermine oxidase | 15862 | 0.93/1.01/0.87/0.56 | 20 | + |
| EPB42 | erythrocyte membrane protein band 4.2 | 3381 | 1.56/1.53/1.31/0.93 | 15 | - |
| KRT1 | keratin 1 | 6412 | 1.94/1.83/2.01/0.82 | 12 | - |
| OSBP2 | oxysterol binding protein 2 | 8504 | 1.24/1.23/1.11/0.70 | 22 | + |
| KLF1 | Kruppel like factor 1 | 6345 | 1.38/1.25/0.94/-0.13 | 19 | - |
| CA1 | carbonic anhydrase 1 | 1368 | 2.42/2.03 /1.97/1.09 | 8 | - |
| IFIT1B | interferon induced protein with tetratricopeptide repeats 1B | 23442 | 1.42/1.24/1.21/1.26 | 10 | + |
| SERPING1 | serpin family G member 1 | 1228 | 0.80/1.66/-0.09/0.17 | 11 | + |
| TSPAN5 | tetraspanin 5 | 17753 | 1.13/1.16/0.91/0.25 | 4 | - |
| TMCC2 | transmembrane and coiled-coil domain family 2 | 24239 | 1.62/1.39/1.14/0.76 | 1 | + |
| HEMGN | hemogen | 17509 | 1.44/1.35/1.28/1.24 | 9 | - |
| FAXDC2 | fatty acid hydroxylase domain containing 2 | 1334 | 1.45/1.32/1.15/1.10 | 5 | - |
| IGF2BP2 | insulin like growth factor 2 mRNA binding protein 2 | 28867 | 1.21/1.03/0.98/1.06 | 3 | - |
| AL356968.2 | amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2 (ALS2CR2) pseudogene | / | 1.58/1.55/1.52/1.03 | 1 | + |
| NFIX | nuclear factor I X | 7788 | 1.29/1.30/1.14/0.61 | 19 | + |
| AL138900.3 | novel transcript | / | 2.91/2.61/2.65/2.06 | 1 | + |
| BMP6 | bone morphogenetic protein 6 | 1073 | 0.70/0.56/0.63/1.26 | 6 | + |
| TNS1 | tensin 1 | 11973 | 1.47/1.25/1.24/1.01 | 2 | - |
| LINC00570 | long intergenic non-protein coding RNA 570 | 43717 | 1.52/1.60 /1.46/0.34 | 2 | + |
| PLA2G16 | phospholipase A2 group XVI | 17825 | -0.48/-0.72/-0.54/-1.51 | 11 | - |
| SOCS1 | suppressor of cytokine signaling 1 | 19383 | 0.12/1.10/0.78/-0.66 | 16 | - |
| ANK1 | ankyrin 1 | 492 | 1.50/1.27/1.18/1.05 | 8 | - |
| STK32C | serine/threonine kinase 32C | 21332 | -0.53/-0.29/-0.49/-1.37 | 10 | - |
| DDX3Y | DEAD-box helicase 3 Y-linked | 2699 | 0 | Y | + |
| ABALON | apoptotic BCL2L1-antisense long non-coding RNA | 49667 | 1.44/1.37/1.66/1.33 | 20 | + |
| MFSD2B | major facilitator superfamily domain containing 2B | 37207 | 1.04/1.08/0.871/0.42 | 2 | + |
| HOMER3 | homer scaffold protein 3 | 17514 | -0.44/-0.24/-0.30/-1.18 | 19 | - |
| LGR6 | leucine rich repeat containing G protein-coupled receptor 6 | 19719 | -1.10/-1.07/-0.70/-0.70 | 1 | + |
| CD274 | CD274 molecule | 17635 | 0.61/1.32 /0.40/0.40 | 9 | + |
| TRIM10 | tripartite motif containing 10 | 10072 | 1.53/1.35 /1.05/0.31 | 6 | - |
| AC104561.3 | novel transcript | / | 1.69/1.66 /1.96/0.48 | 8 | - |
| PEAR1 | platelet endothelial aggregation receptor 1 | 33631 | 0.83/0.77/0.76/1.62 | 1 | + |
| BBOF1 | basal body orientation factor 1 | 19855 | 1.29/1.31 /1.34/1.12 | 14 | + |
| EIF1AY | eukaryotic translation initiation factor 1A Y-linked | 3252 | 0 | Y | + |
| SMIM5 | small integral membrane protein 5 | 40030 | 1.16/1.28/0.95/-0.18 | 17 | + |
| XK | X-linked Kx blood group | 12811 | 0.91/0.88/0.61/1.04 | X | + |
| SPTB | spectrin beta, erythrocytic | 11274 | 1.06/0.94/0.75/1.49 | 14 | - |
| KDM5D | lysine demethylase 5D | 11115 | 0 | Y | - |
| GYPB | glycophorin B (MNS blood group) | 4703 | 2.11/2.14/1.94/1.56 | 4 | - |
| PRKY | protein kinase Y-linked (pseudogene) | 9444 | -8.75/-9.06/-9.06/-8.43 | Y | + |
| XIST | X inactive specific transcript | 12810 | † | X | - |
| LINC00189 | long intergenic non-protein coding RNA 189 | 18461 | 0.63/2.05/1.12/0.14 | 21 | + |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 12638 | 0 | Y | - |
| AP000787.1 | uncharacterized LOC101929295 [Source:NCBI gene;Acc:101929295] | / | 1.62/1.32 /1.45/1.13 | 11 | + |
| MARCH3 | membrane associated ring-CH-type finger 3 | 28728 | 1.55/1.48/1.13/-0.27 | 5 | - |
| CMBL | Carboxy methylene buteno lidase homolog | 25090 | 1.61/1.70/1.65/1.13 | 5 | - |
| TMSB4Y | thymosin beta 4 Y-linked | 11882 | 0 | Y | + |
| TXLNGY | taxilin gamma pseudogene, Y-linked | 18473 | 0 | Y | + |
| GIPC3 | GIPC PDZ domain containing family member 3 | 18183 | 1.13/0.81 /0.79/1.45 | 19 | + |
| USP9Y | ubiquitin specific peptidase 9 Y-linked | 12633 | 0 | Y | + |
| ZFY | zinc finger protein Y-linked | 12870 | 0 | Y | + |
| ABCC13 | ATP binding cassette subfamily C member 13 (pseudogene) | 16022 | 2.11/1.64/1.81/1.00 | 21 | + |
| ZP3 | zona pellucida glycoprotein 3 | 13189 | -0.51/0.05/0.01/-1.89 | 7 | + |
| HSD3B7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 18324 | 0.59/1.26/0.61/-0.49 | 16 | + |
| MFSD6L | major facilitator superfamily domain containing 6 like | 26656 | 0.54/1.44/0.65/1.23 | 17 | - |
| LINC00278 | long intergenic non-protein coding RNA 278 | 38712 | 0 | Y | + |
| AC010615.2 | uncharacterized LOC105372321 [Source:NCBI gene;Acc:105372321] | / | 2.54/2.01 /2.29/1.07 | 19 | - |
| TTTY15 | testis-specific transcript, Y-linked 15 | 18567 | 0 | Y | + |
| RARRES2P4 | retinoic acid receptor responder 2 pseudogene 4 | 48703 | 4.45/0.38/-0.69/-0.59 | 4 | - |
| AL157756.1 | uncharacterized LOC101927702 [Source:NCBI gene;Acc:101927702] | / | 1.25/1.14/0.57/0.45 | 14 | - |
| AC114811.2 | novel transcript, antisense TSPAN5 | / | 2.03/1.30/0.88/1.06 | 4 | + |
| TMEM56 | transmembrane protein 56 | 26477 | 1.73/1.05/1.44/0.76 | 1 | + |
| AC010889.1 | novel transcript | / | 0 | Y | - |
| LPL | lipoprotein lipase | 6677 | -0.95/-1.49/-1.80/-0.98 | 8 | + |
| ANOS2P | anosmin 2, pseudogene | 6214 | 0 | Y | + |
| BCORP1 | BCL6 corepressor pseudogene 1 | 23953 | 0 | Y | - |
| TDRD6 | tudor domain containing 6 | 21339 | -0.32/-0.81/-1.526/0.14 | 6 | + |
| TTTY14 | testis-specific transcript, Y-linked 14 | 18495 | 0 | Y | - |
| NLGN4Y | neuroligin 4 Y-linked | 15529 | 0 | Y | + |
Note: The values of Log2|FoldChange| column including expression level were compared between females and males at four different time points (Day 0, Day 03, Day 28, Day 180), ‘0' represented the transcripts only detected in males on Y chromosome, and '†' indicated the transcript only detected in females on X chromosome.