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. 2021 Apr 2;13(7):9398–9418. doi: 10.18632/aging.202912

Table 3. Changes in physical function in the two groups.

Δ12 weeks Time effect Time*treatment interaction
Novel supplement (n=40) P-value Standard supplement
(n=41)
P-valuea
Walking performance 4 mb -0.4 ± 0.1 s 0.047 0.0 ± 0.1 s 1.000 0.044 0.048
400 mc -7.4 ± 8.7 s 1.000 17.6 ± 7.8 s 0.172 0.386 0.038
Handgrip Strengthb Dom 0 ± 1 kg 1.000 0 ± 1 kg 1.000 0.974 0.948
Non-dom 0 ± 1 kg 1.000 1 ± 1 kg 1.000 0.660 0.340
Knee extensiond Dom -2 ± 14 N 1.000 26 ± 21 N 1.000 0.200 0.145
Non-dom 8 ± 12 N 1.000 38 ± 10 N 0.003 0.005 0.058
Knee flexiond Dom 12 ± 9 N 1.000 23 ± 8 N 0.036 0.006 0.351
Non-dom 6 ± 10 N 1.000 15 ± 8 N 0.443 0.106 0.453
Chair rise testc 0.0 ± 0.5 s 1.000 -0.3 ± 0.4 s 1.000 0.543 0.634
SPPB score 0.1 ± 0.2 pt 1.000 0.3 ± 0.2 pt 0.523 0.169 0.355

Dom, dominant limb; non-dom, non-dominant limb; N, Newton; SPPB, short physical performance battery.

aP-values are from posthoc tests with Bonferroni adjustment of multiple testing.

bAdjusted for gender and height.

cAdjusted for gender, height and age.

dAdjusted for gender, height, age and observer.