Table 1. All antibodies used in this study were showed.

Primary antibodies
Anti-Target	Abbreviation	Host	Company and source	Catalog number	Application
activity-regulated cytoskeleton-associated protein/activity-regulated gene 3.1	Arc/Arg 3.1	Rabbit	Proteintech Wuhan, China	16290-1-AP	WB(1:1000), IHC(1:200)
c-Fos	c-Fos	Mouse	Servicebio Wuhan, China	GB12069	WB(1:1000), IHC(1:200)
NeuN	NeuN	Rabbit	Servicebio Wuhan, China	GB11138	IF(1:200)
microtubule-associated protein 2	MAP2	Rabbit	Proteintech Wuhan, China	17490-1-AP	WB(1:1000), IHC(1:200)
Developmentally-regulated brain protein	drebrin	Rabbit	Servicebio Wuhan, China	GB111519	WB(1:500)
phopsphorylated cofilin	p-cofilin	Rabbit	Cell signaling Beverly, MA, USA	3313	WB(1:1000)
total cofilin	t-cofilin	Rabbit	Cell signaling Beverly, MA, USA	5175	WB(1:1000)
phopsphorylated LIM kinases1	p-LIMK1	Rabbit	abcam Cambridge, CB, UK	ab194798	WB(1:1000)
total LIM kinases1	t-LIMK1	Rabbit	Cell signaling Beverly, MA, USA	3842	WB(1:1000)
Fyn	Fyn	Rabbit	abcam Cambridge, CB, UK	ab125016	WB(1:1000)
phopsphorylated p21-activated kinase1	p-PAK1	Rabbit	abcam Cambridge, CB, UK	ab75599	WB(1:1000)
total p21-activated kinase1	t-PAK1	Rabbit	Cell signaling Beverly, MA, USA	2602	WB(1:1000)
total Rac1	Rac1	Rabbit	Cell signaling Beverly, MA, USA	4651	WB(1:1000)
N-methyl D-aspartate receptor 1	NR1	Rabbit	Proteintech Wuhan, China	27676-1-AP	WB(1:1000)
N-methyl D-aspartate receptor 2	NR2A/2B	Rabbit	Millipore Billerica, MA, USA	ab65783	WB(1:1000)
synaptophysin	synaptophysin	Rabbit	Servicebio Wuhan, China	GB11553	WB(1:1000)
Postsynaptic Density protein 95	PSD95	Mouse	Cell signaling Beverly, MA, USA	36233	WB(1:1000)
myelin basic protein	MBP	Rabbit	Servicebio Wuhan, China	GB11226	WB(1:1000)
phosphorylated mTor	p-mTor	Rabbit	Cell signaling Beverly, MA, USA	5536	WB(1:1000)
total mTor	t-mTor	Rabbit	Cell signaling Beverly, MA, USA	2983	WB(1:1000)
phosphorylated p70S6K	p-p70S6K	Rabbit	Cell signaling Beverly, MA, USA	9204	WB(1:1000)
total p70S6K	t-p70S6K	Rabbit	Cell signaling Beverly, MA, USA	2708	WB(1:1000)
phosphorylated 4EBP-1	p-4EBP-1	Rabbit	Cell signaling Beverly, MA, USA	9459	WB(1:1000)
total 4EBP-1	t-4EBP-1	Rabbit	Cell signaling Beverly, MA, USA	9452	WB(1:1000)
phosphorylated eEF2	p-eEF2	Rabbit	Cell signaling Beverly, MA, USA	2331	WB(1:1000)
total eEF2	t-eEF2	Rabbit	Cell signaling Beverly, MA, USA	2332	WB(1:1000)
β-actin	β-actin	Mouse	Cell signaling Beverly, MA, USA	3700	WB(1:1000)
Secondary antibodies
Anti- Target	Host	Label	Company	Catalog number	Application
Rabbit IgG	Goat	Biotin	Zsbio Beijing, China	SAP-9101	IHC(1:100)
Mouse IgG	Goat	Biotin	Zsbio Beijing, China	SP-9102	IHC(1:100)
Rabbit IgG	Goat	IRDye™ (800CW)	Licor Lincoln, NE, USA	AB_2651127	WB(1:10000)
Mouse IgG	Goat	IRDye™ (800CW)	Licor Lincoln, NE, USA	AB_2687825	WB(1:10000)
Rabbit IgG	Goat	Alexa Fluor 488	Cell signaling Beverly, MA, USA	4412	IF(1:1000)
Mouse IgG	Goat	Alexa Fluor 488	Cell signaling Beverly, MA, USA	4408	IF(1:1000)