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. 2021 Mar 19;13(7):9330–9347. doi: 10.18632/aging.202705

Table 3. Physical function improvements at 3-month and 6-month interventions in sarcopenia versus non-sarcopenia elderly.

All subjects (n = 242) Sarcopenic subgroups
Sarcopenia (n = 92) Non-Sarcopenia (n = 150) t p
Lower limb strength, kg
 Baseline (0M) 14.17 ± 5.01 12.27 ± 3.11 15.33 ± 5.57 –5.491 <0.001
 3 Month (3M) 15.71 ± 5.76*** 13.93 ± 4.13*** 16.75 ± 6.31** –4.132 <0.001
 6 Month (6M) 16.04 ± 5.50*** 14.08 ± 4.71*** 17.17 ± 5.61*** –4.256 <0.001
 Change (3M-0M)% 15.57 ± 38.15 17.47 ± 36.55 14.47 ± 39.12 0.580
 Change (6M-0M)% 18.28 ± 36.22 19.05 ± 38.46 17.84 ± 34.99 0.243
 F, p 19.612, <0.001 10.160, <0.001 11.343, <0.001
ASMI, kg/m2
 Baseline (0M) 6.11 ± 1.07 5.32 ± 0.82 6.60 ± 0.90 –11.092 <0.001
 3 Month (3M) 6.21 ± 1.07** 5.37 ± 0.74 6.66 ± 0.95* –10.603 <0.001
 6 Month (6M) 6.21 ± 1.09*** 5.35 ± 0.76** 6.68 ± 0.95 –10.802 <0.001
 Change (3M-0M)% 1.65 ± 6.18 2.20 ± 6.84 1.35 ± 5.80 0.928
 Change (6M-0M)% 1.69 ± 5.82 1.73 ± 7.04 1.68 ± 5.06 0.051
 F, p 8.104, <0.001 6.486, 0.002 3.513, 0.035
Gait speed, second
 Baseline (0M) 5.61 ± 1.65 5.76 ± 1.76 5.52 ± 1.57 1.074 0.284
 3 Month (3M) 4.84 ± 1.23*** 4.72 ± 1.01*** 4.85 ± 1.33*** –0.834 0.405
 6 Month (6M) 4.84 ± 1.01*** 4.92 ± 1.02*** 4.79 ± 1.00*** 0.942 0.347
 Change (3M-0M)% –10.43 ± 24.17 –13.29 ± 23.56 –8.79 ± 24.44 –1.378
 Change (6M-0M)% –9.04 ± 24.45 –9.37 ± 26.11 –8.85 ± 23.53 –0.155
 F, p 28.155, <0.001 13.688, <0.001 16.408, <0.001

Abbreviations: ASMI = Appendicular skeletal muscle index. *p < 0.05, **p < 0.01, ***p < 0.001 vs. baseline level.