Table 3. Comparison of various diagnostic parameters of T-SPOT.TB, MRI, and combination tests (n = 229).

	Sensitivity (%)	Specificity (%)	PPV	NPV	LR+	LR-	Accuracy (%)
T-SPOT.TB	0.73	0.69	0.61	0.79	2.35	0.39	0.71
MRI	0.60	0.91	0.82	0.77	6.83	0.44	0.79
Serial test	0.47	0.97#	0.91	0.73	16.01	0.55	0.77
Parallel test	0.86*	0.65	0.62	0.87	2.45	0.22	0.73

PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR-, negative likelihood ratio; ^#Comparison of the specificity between T-SPOT.TB and Serial test, P=0.007, comparison of the specificity between MRI and Serial test, P<0.001; *Comparison of the sensitivity between T- SPOT.TB and Parallel test, P<0.001, comparison of the sensitivity among MRI and Parallel test, P<0.001.