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. 2021 Apr 23;16(1):26. doi: 10.5334/gh.973

Table 1.

Analysis of antihypertensive drug sales in the private pharmaceutical market in India and five states in 2018: Defined daily dose (DDD) per 1000 hypertensive adults per day and estimated proportion of adults with hypertension receiving antihypertensive drugs per day.

Indicators State-level All-India

Kerala Maharashtra Telangana Punjab Madhya Pradesh

a. Total anti-hypertensive drug sales (pills in million)* 1800 3669 842 729 805 22,175
b. Total sales of single molecule drugs in DDDs (in million)* 1058 1630 347 337 332 10,312
c. Total sales of FDCs in DDDs (in million)* 370 1502 360 299 377 8,675
d. Prevalence of hypertension among adults (18+ years) 34.5% 24.8% 20% 34.8% 21.9% 25.3%
e. Estimated number of adults with hypertension in 2018 (in million) 8.9 21.2 5.2 7.4 11.1 220.4
A. DDDs per 1000 adults with hypertension per day 441 404 372 234 175 236
B. Proportion of estimated adult hypertensive population receiving anti-hypertensive drugs per day 38.7% 36.9% 34.2% 21.4% 16.1% 21.5%

Note:

* Volume of sales adjusted for 100% sales against 95% coverage of the data set.

Calculations:

  1. DDDs per 1000 adults with hypertension per day in 2018 is calculated by dividing total sales in DDDs by the estimated number of adults with hypertension as per the following formula:
    A = (b+c)/e * (1000/365)
  2. Proportion of estimated adult population with hypertension receiving antihypertensive drugs per day in 2018 is calculated using a prescription scenario of (PDD:DDD = 1.2) for single molecule drugs and (PDD:DDD = 1) for fixed-dose combination (FDC) drugs as per the following formula:
    B = [(b/1.2)+c]/e * (100/365)