Table 1.
Selection of myocardial infarction relevant matrix metalloproteinase 9 (MMP-9) derived matricryptins.
ECM Parent Protein | ECM-Fragment | Effect on Cardiac Wound Healing | Reference |
---|---|---|---|
Collagen I | C-1158/59 | Stimulates neovascularization | [65] |
Collagen IV | Tumstatin | Inhibits angiogenesis | [66] |
Collagen XVIII | Endostatin | Inhibits angiogenesis | [67,68] |
Osteopontin (OPN) | OPN-p151 OPN-p152 |
Increases fibroblast migration and wound healing | [69] |
ECM: Extracellular matrix; OPN: osteopontin.