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. 2021 Mar 25;10(4):260. doi: 10.3390/biology10040260

Table 4.

Thickness of selected macular layers is reduced in glaucoma patients compared to healthy controls.

Macular Segment Thickness Glaucoma Healthy p-Value 1
Mean ± SD Mean ± SD
Ganglion cell layer (GCL)
Central (C0) 20.8 ± 8.6 19.4 ± 7.9 0.62
Inner superior (S1) 44.1 ± 11.3 52.2 ± 6.2 0.0002
Outer superior (S2) 29.6 ± 5.8 33.9 ± 3.5 0.0002
Inner nasal (N1) 45.1 ± 12.9 52.9 ± 5.9 0.0006
Outer nasal (N2) 31.2 ± 7.8 36.4 ± 4.7 0.001
Inner inferior (I1) 42.8 ± 11.8 51.2 ± 7.0 0.0004
Outer inferior (I2) 28.6 ± 5.9 33.2 ± 4.2 0.0005
Inner temporal (T1) 40.5 ± 12.4 46.8 ± 6.0 0.0047
Outer temporal (T2) 29.3 ± 7.9 36.5 ± 4.6 <0.0001
Inner plexiform layer (IPL)
Central (C0) 23.4 ± 7.1 23.2 ± 5.3 0.93
Inner superior (S1) 37.0 ± 6.7 40.7 ± 4.4 0.0089
Outer superior (S2) 25.2 ± 4.1 27.4 ± 3.0 0.015
Inner nasal (N1) 40.3 ± 6.1 42.3 ± 2.9 0.061
Outer nasal (N2) 26.1 ± 4.7 27.9 ± 3.3 0.079
Inner inferior (I1) 35.5 ± 8.4 40.1 ± 4.7 0.0046
Outer inferior (I2) 24.2 ± 4.3 26.4 ± 3.4 0.024
Inner temporal (T1) 36.9 ± 8.7 40.1 ± 4.1 0.040
Outer temporal (T2) 28.3 ± 5.7 31.7 ± 3.1 0.0019
Retina
Central (C0) 287.1 ± 31.5 281.3 ± 28.9 0.47
Inner superior (S1) 331.2 ± 25.9 343.3 ± 14.7 0.015
Outer superior (S2) 289.0 ± 21.1 301.4 ± 15.2 0.0078
Inner nasal (N1) 338.5 ± 20.1 346.5 ± 13.9 0.065
Outer nasal (N2) 305.6 ± 29.9 316.5 ± 17.1 0.060
Inner inferior (I1) 323.3 ± 26.8 339.5 ± 21.5 0.010
Outer inferior (I2) 277.6 ± 21.6 293.7 ± 18.2 0.0024
Inner temporal (T1) 318.4 ± 25.2 327.5 ± 13.8 0.057
Outer temporal (T2) 274.9 ± 18.0 288.2 ± 16.3 0.0041

1p-values of t-test or Mann–Whitney U test (when appropriate) significant when p < 0.05 (bold, underlined). Abbreviations: SD: standard deviation.