Table 5.

The thickness of the pRNFL and of selected macular layer subfields correlate with the presence of glaucoma.

Sector/Subfield	Coefficient	95% CI	OR	R2	p-Value 1	AUC	95% CI
Peripapillary retinal nerve fibre layer (pRNFL)
Multivariate logistic regression
All sectors				0.39	<0.0001	0.83	0.71–0.96
Univariate logistic regression
Superior	−0.12	−0.20–−0.057	0.89	0.30	0.0011	0.75	0.60–0.90
Temporal superior (TS)	−0.046	−0.080–−0.020	0.96	0.21	0.0021	0.67	0.51–0.83
Nasal superior (NS)	−0.047	−0.080–−0.023	0.95	0.26	0.0010	0.72	0.57–0.88
Nasal	−0.029	−0.055–−0.0066	0.97	0.11	0.0169	0.61	0.44–0.78
Inferior	−0.035	−0.076–0.0025	0.97	0.054	0.077	0.63	0.47–0.79
Nasal inferior (NI)	−0.076	−0.13–−0.039	0.93	0.33	0.0005	0.81	0.69–0.93
Temporal superior (TI)	−0.042	−0.071–−0.017	0.96	0.18	0.0023	0.73	0.59–0.88
Temporal	−0.067	−0.11–−0.034	0.94	0.33	0.0007	0.81	0.69–0.93
Superior	−0.053	−0.11–−0.0054	0.95	0.079	0.0429	0.64	0.48–0.80
mRNFL-GCL-IPL
multivariate logistic regression
Superior and inferior subfields (S1, S2, I1, I2)				0.42	<0.0001	0.85	0.73–0.97
Macular retinal nerve fibre layer (mRNFL)
Univariate logistic regression
Inner superior (S1)	−0.027	−0.14–0.016	0.97	0.010	0.31	0.53	0.36–0.70
Outer superior (S2)	−0.11	−0.20–−0.028	0.90	0.13	0.0048	0.64	0.47–0.82
Inner inferior (I1)	−0.028	−0.14–0.011	0.91	0.013	0.25	0.54	0.37–0.70
Outer inferior (I2)	−0.090	−017–−0.027	0.91	0.14	0.0030	0.68	0.52–0.84
Ganglion cell layer (GCL)
Univariate logistic regression
Inner superior (S1)	−0.11	−0.20–−0.045	0.89	0.18	0.0006	0.74	0.60–0.89
Outer superior (S2)	−0.22	−0.37–−0.091	0.8	0.19	0.0004	0.71	0.57–0.86
Inner inferior (I1)	−0.098	−0.17–−0.039	0.91	0.17	0.0009	0.75	0.60–0.89
Outer inferior (I2)	−0.2	−0.35–−0.084	0.81	0.19	0.0005	0.76	0.62–0.89
Inner plexiform layer (IPL)
Univariate logistic regression
Inner superior (S1)	−0.12	−0.25–−0.026	0.88	0.096	0.0126	0.66	0.51–0.80
Outer superior (S2)	−0.19	−0.37–−0.033	0.83	0.086	0.0173	0.67	0.52–0.83
Inner inferior (I1)	−0.11	−0.22–−0.030	0.89	0.11	0.0072	0.67	0.50–0.84
Outer inferior (I2)	−0.17	−0.34–−0.022	0.84	0.08	0.0233	0.68	0.53–0.83

¹p-values for the coefficient of the log-likelihood ratio test of logistic regression analysis, statistically significant when p < 0.05 (bold, underlined). Abbreviations: 95% CI: 95% confidence interval; OR: odds’ ratio; R²: Tjur’s pseudo R² factor; AUC: area under the receiver operating characteristic curve.