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. 2021 Mar 25;10(4):260. doi: 10.3390/biology10040260

Table 6.

Sensitivity and specificity of selected pRNFL and macular areas.

Sector/Subfield Sensitivity at
Specificity ≥ 80% Specificity ≥ 90% Specificity ≥ 95%
Peripapillary retinal nerve fibre layer (pRNFL)
Multivariate logistic regression
All sectors 74% 74% 63%
Univariate logistic regression
Average 63% 53% 42%
Superior 53% 42% 42%
Inferior 68% 58% 42%
mRNFL–GCL–IPL
Multivariate logistic regression
Superior and inferior subfields (S1, S2, I1, I2) 74% 68% 63%
Macular retinal nerve fibre layer (mRNFL)
univariate logistic regression
Inner superior (S1) 42% 21% 11%
Outer superior (S2) 53% 47% 42%
Inner inferior (I1) 32% 21% 11%
Outer inferior (I2) 47% 37% 26%
Ganglion cell layer (GCL)
univariate logistic regression
Inner superior (S1) 63% 32% 32%
Outer superior (S2) 47% 42% 42%
Inner inferior (I1) 63% 42% 26%
Outer inferior (I2) 58% 47% 42%
Inner plexiform layer (IPL)
univariate logistic regression
Inner superior (S1) 32% 26% 26%
Outer superior (S2) 58% 37% 16%
Inner inferior (I1) 42% 37% 32%
Outer inferior (I2) 47% 37% 16%