Table 3.

Pairwise comparison of groups II–V to group I by the miRNA ΔCt value for an optimized cohort of patients.

miRNA	Group	Ме	Q1	Q3	Mann–Whitney Test, p-Value	Bonferroni Adjustments for 20 Tests (5 miRNAs & 4 Comparisons), p-Value
miR-17-5p	I	10.95	6.23	11.04
miR-17-5p	IIa + IIb	11.07	10.87	11.19	0.055163	1
miR-17-5p	III	8	6.51	10.85	0.135911	1
miR-17-5p	IV	7.02	5.44	10.75	0.040858	0.81716
miR-17-5p	V	9.67	5.24	9.75	0.054895	1
miR-21-5p	I	10.89	7.23	11.03
miR-21-5p	IIa + IIb	8.55	7.4	11.06	0.725852	1
miR-21-5p	III	5.2	4.42	5.93	<0.0001	0.0198
miR-21-5p	IV	5.39	4.46	5.89	<0.0001	<0.0001
miR-21-5p	V	0.67	0.4	0.99	0.000175	0.0035
miR-25-3p	I	7.28	6.33	8.53
miR-25-3p	IIa + IIb	8.77	7.11	10.87	0.317547	1
miR-25-3p	III	5.94	5.06	6.35	0.077005	1
miR-25-3p	IV	6.34	4.71	9.45	0.289503	1
miR-25-3p	V	1.65	0.91	2.09	0.000175	0.0035
miR-320a-3p	I	4	3.39	4.49
miR-320a-3p	IIa + IIb	3.91	3.66	4.66	0.815253	1
miR-320a-3p	III	2.75	2.29	2.94	0.000494	0.00988
miR-320a-3p	IV	2.84	2.6	3.22	<0.0001	0.00092
miR-320a-3p	V	1.01	0.92	1.69	0.000175	0.0035
miR-92a-3p	I	3.74	3.71	4.04
miR-92a-3p	IIa + IIb	4.17	3.75	4.4	0.215228	1
miR-92a-3p	III	2.82	2.61	3	0.000165	0.0033
miR-92a-3p	IV	2.98	2.62	3.64	0.025147	0.50294
miR-92a-3p	V	−0.01	−0.58	0.48	0.000175	0.0035

Data are presented as the median (Me) of the ΔCt values and quartiles Q1 and Q3 and the statistical significance of the differences p while applying Mann–Whitney test with Bonferroni correction for multiple testing.