Table 4.
Holm–Bonferroni test for pairwise comparison of groups II–V to group I by the miRNA ΔCt value from Table 3.
| miRNA | I vs. II, Mann–Whitney Test, p-Value | Order | Holm–Bonferroni Test, p-Value | Significance 1 |
| miR-17-5p | 0.05516 | 1 | 0.01000 | 0 |
| miR-92a-3p | 0.21523 | 2 | 0.01250 | 0 |
| miR-25-3p | 0.31755 | 3 | 0.01667 | 0 |
| miR-21-5p | 0.72585 | 4 | 0.02500 | 0 |
| miR-320a-3p | 0.81525 | 5 | 0.05000 | 0 |
| miRNA | I vs. III, Mann–Whitney Test, p-Value | Order | Holm–Bonferroni Test, p-Value | Significance 1 |
| miR-21-5p | 0.0001 | 1 | 0.01000 | 1 |
| miR-92a-3p | 0.0002 | 2 | 0.01250 | 1 |
| miR-320a-3p | 0.0005 | 3 | 0.01667 | 1 |
| miR-25-3p | 0.0770 | 4 | 0.02500 | 0 |
| miR-17-5p | 0.1359 | 5 | 0.05000 | 0 |
| miRNA | I vs. IV, Mann–Whitney Test, p-Value | Order | Holm–Bonferroni Test, p-Value | Significance 1 |
| miR-21-5p | 0.00010 | 1 | 0.01000 | 1 |
| miR-320a-3p | 0.00010 | 2 | 0.01250 | 1 |
| miR-92a-3p | 0.02515 | 3 | 0.01667 | 0 |
| miR-17-5p | 0.04086 | 4 | 0.02500 | 0 |
| miR-25-3p | 0.28950 | 5 | 0.05000 | 0 |
| miRNA | I vs. V, Mann–Whitney Test, p-Value | Order | Holm–Bonferroni Test, p-Value | Significance 1 |
| miR-21-5p | 0.00018 | 1 | 0.01000 | 1 |
| miR-92a-3p | 0.00018 | 2 | 0.01250 | 1 |
| miR-320a-3p | 0.00018 | 3 | 0.01667 | 1 |
| miR-25-3p | 0.00018 | 4 | 0.02500 | 1 |
| miR-17-5p | 0.05490 | 5 | 0.05000 | 0 |
1 “1” means statistically significant difference, “0” means insignificant difference.