Table 8.
Deep sequencing data on miRNA expression level in the placenta in the area outside of pathological invasion (N-area).
| miRNA 1 | III_N1 | III_N2 | III_N3 | IV_N4 | IV_N5 | IV_N8 | V_N6 | V_N7 | FC (IV/III) | FC (V/III) | p (IV vs. III) | p (V vs. III) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| miR-17-5p | 301 | 218 | 212 | 208 | 741 | 1122 | 767 | 389 | 3.4 | 2.7 | 0.104 | 0.048 |
| miR-21-5p | 8290 | 6505 | 6265 | 11,066 | 17,856 | 15,617 | 26,978 | 7142 | 2.4 | 2.6 | 0.158 | 0.064 |
| miR-25-3p | 2451 | 1716 | 1222 | 1211 | 40,054 | 84,350 | 49,601 | 2940 | 23.3 | 15.3 | <0.001 | <0.001 |
| miR-92a-3p | 15,612 | 18,053 | 27,168 | 22,394 | 288,269 | 722,332 | 647,513 | 14,940 | 16.0 | 18.3 | <0.001 | 0.002 |
| miR-320a-3p | 6485 | 8611 | 10,781 | 15,287 | 30,893 | 22,918 | 29,831 | 5513 | 2.7 | 2.1 | 0.075 | 0.191 |
1 III, IV, and V are the group numbers; P1–P8 are the numbers of placental samples from the N-area; FC is the fold change in the expression level as the ratio of the medians of the miRNA read numbers in the compared groups; p—statistical significance of differences.