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Compositional changes induced by sugar stress. Principal component analysis (PCA) expressed by the two most decisive variables (PC1 and PC2) accounting for approx. 27% of the variation of the dataset in the sucrose and placebo group. (A) baseline vs. week 2. (B) week 2 vs. week 5. (C) baseline vs. week 5. Linear discriminant analysis effect size (LEfSe) analysis expressed by significant genera (D) and species (E).
