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miR-21-5p and miR-100-5p mediate oxPAPC effects on VEGFA/MYC pathway. (A) miRNA-target network from miRNet.36,37 (B) Illustration of VEGF/MYC pathway. (C) Effects of miR-21-5p overexpression and miR-100-5p inhibition on MTOR, HIF1A, VEGFA, and MYC expressions. (n = 3, mean ± SD, unpaired two-tailed t-test, ****P < 0.0001, ***P < 0.001).
