Figure 1.

Standard pharmacologic management of Clostridioides difficile infection. A suggested regimen for vancomycin taper is as follows: 125 mg orally four times daily for 10–14 days, 125 mg orally two times daily for 7 days, 125 mg orally once daily for 7 days, and 125 mg orally every 2 or 3 days for 2–8 weeks. A rifaximin chaser regimen involves vancomycin 125 mg orally four times daily for 10 days followed by rifaximin 400 mg three times daily for 10 days.

Printed with permission from Cho et al.¹¹ Mayo Clin Proc 2020; 95: 758–769.

bid, twice a day; FMT, fecal microbiota transplantation; IV, intravenously; po, orally; qid, four times a day; tid, three times a day.