Figure 2.

LINC00184 facilitated proliferation and cisplatin resistance, and inhibited apoptosis of OC cells and cisplatin-resistant OC cells. (A) After transfection, qRT-PCR was used to detect the transfection efficiency of OC cells. **p<0.01 compared with the siNC group or oeNC group. (B) CCK-8 assay was used to detect cisplatin resistance in OC cells. The IC₅₀ was calculated using the LOGIT method. (C) CCK-8 assay for A2780-DDP and SKOV3-DDP cell proliferation. **p<0.01 compared with the siNC group. ##p<0.01 compared with the siNC + cisplatin group. (D) CCK-8 assay for A2780 and SKOV3 cell proliferation. **p<0.01 compared with the oeNC group. ##p<0.01 compared with the oeNC + cisplatin group. (E) Flow cytometry for A2780-DDP and SKOV3-DDP cell apoptosis. **p<0.01, #p<0.05 and ##p<0.01 compared with the siNC group. ^^p<0.01 compared with the siNC + cisplatin group. (F) Flow cytometry for A2780 and SKOV3 cell apoptosis. **p<0.01 and ##p<0.01 compared with the oeNC group. ^^p<0.01 compared with the oeNC + cisplatin group. All experiments were performed in triplicate.