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. 2021 Apr 23;16(4):e0247359. doi: 10.1371/journal.pone.0247359

Table 3. Independent predictors for non-target lesion revascularization.

Variable Univariate analysis Multivariate analysis
HR 95% CI p-value HR 95% CI p-value
Age 0.988 0.956–1.022 0.487 0.985 0.947–1.023 0.432
Male 0.880 0.450–1.722 0.710 1.240 0.550–2.798 0.604
Diabetes 1.830 0.947–3.536 0.072 1.618 0.796–3.286 0.184
Hypertension 1.284 0.630–2.617 0.492
Dyslipidemia 0.765 0.392–1.494 0.433
Current smoker 1.496 0.735–3.048 0.267
CKD 8.451 2.497–28.606 0.001 8.730 2.175–35.036 0.002
History of MI 3.210 0.756–13.632 0.114
DCB angioplasty after OCT 1.317 0.615–2.823 0.478
First-generation DES 0.986 0.489–1.991 0.970
Homogeneous neointima 0.604 0.310–1.177 0.139
Heterogeneous neointima 2.024 1.025–4.000 0.042 2.237 1.023–4.890 0.044
Layered neointima 0.852 0.349–2.082 0.726
ACEi or ARB 0.891 0.416–1.907 0.766
Beta blocker 0.538 0.269–1.078 0.080 0.901 0.387–2.096 0.809
Statin 1.004 0.303–3.325 0.995

ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor antagonist; CKD, chronic kidney disease, CI, confidence interval; DCB, drug-coated balloon; DES, drug-eluting stent; MI, myocardial infarction; OCT, optical coherence tomography; HR, hazard ratio