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. 2021 Apr 23;16(4):e0247359. doi: 10.1371/journal.pone.0247359

Table 4. Independent predictors for any revascularization.

Variable Univariate analysis Multivariate analysis
HR 95% CI p-value HR 95% CI p-value
Age 0.994 0.968–1.020 0.633 0.978 0.950–1.007 0.132
Male 0.643 0.383–1.078 0.094 0.770 0.426–1.392 0.386
Diabetes 1.847 1.111–3.070 0.018 1.524 0.897–2.592 0.119
Hypertension 0.833 0.492–1.411 0.497
Dyslipidemia 0.838 0.499–1.408 0.505
Current smoker 1.259 0.716–2.213 0.424
CKD 6.354 2.253–17.920 <0.001 5.971 1.902–18.751 0.002
History of MI 1.439 0.349–5.927 0.614
DCB angioplasty after OCT 2.430 1.406–4.203 0.001
First-generation DES 1.043 0.609–1.788 0.877
Homogeneous neointima 0.301 0.169–0.537 <0.001 0.505 0.222–1.150 0.104
Heterogeneous neointima 4.324 2.537–7.370 <0.001 2.671 1.261–5.656 0.010
Layered neointima 0.820 0.411–1.637 0.574
ACEi or ARB 0.741 0.417–1.316 0.306
Beta blocker 0.434 0.251–0.752 0.003 0.745 0.403–1.378 0.348
Statin 0.856 0.365–2.006 0.720

ACEi, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor antagonist; CI, confidence interval; CKD, chronic kidney disease; DCB, drug-coated balloon; DES, drug-eluting stent; MI, myocardial infarction; OCT, optical coherence tomography; HR, hazard ratio