Table 2.
Clinical, pathologic, and treatment-related characteristics of the EBRT and boost-IORT groups.
| EBRT | Electron boost | X-ray -boost | Total | ||||||
|---|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | N | % | ||
| 657 | 100 | 706 | 100 | 283 | 100 | 1646 | 100 | ||
| Stage | |||||||||
| 1 | 89 | 13.50 | 132 | 19 | 30 | 10.60 | 251 | 24.70 | |
| 2 | 428 | 65.10 | 430 | 61.80 | 168 | 59.40 | 1026 | 57.40 | |
| 3 | 140 | 21.30 | 134 | 19.30 | 85 | 30 | 359 | 17.90 | |
| Total | 657 | 100 | 696 | 100 | 283 | 100 | 1636 | 100 | |
|
| |||||||||
| Size | |||||||||
| ≤2.5 cm | 312 | 53.10 | 374 | 58.30 | 115 | 42.40 | 801 | 60.00 | |
| 2.5 = 3 cm | 144 | 24.50 | 99 | 15.40 | 39 | 14.40 | 282 | 17.00 | |
| >3 cm | 132 | 22.40 | 169 | 26.30 | 117 | 43.20 | 418 | 23.10 | |
| Total | 588 | 100 | 642 | 100 | 271 | 100 | 1501 | 100 | |
|
| |||||||||
| Grade | |||||||||
| 1 | 54 | 8.60 | 47 | 7.00 | 31 | 12.30 | 132 | 10.30 | |
| 2 | 336 | 53.40 | 379 | 56.80 | 97 | 38.30 | 812 | 53.50 | |
| 3 | 239 | 38 | 241 | 36.10 | 125 | 49.40 | 605 | 36.20 | |
| Total | 629 | 100 | 667 | 100 | 253 | 100 | 1549 | 100 | |
|
| |||||||||
| LVI | |||||||||
| Positive | 254 | 42 | 328 | 49.90 | 118 | 72.40 | 700 | 43.00 | |
| Negative | 351 | 58 | 329 | 50.10 | 45 | 27.60 | 725 | 57.00 | |
| Total | 605 | 100 | 657 | 100 | 163 | 100 | 1425 | 100 | |
|
| |||||||||
| Ki67 | |||||||||
| >30% | 32 | 11.80 | 176 | 29.00 | 23 | 35.90 | 231 | 27.10 | |
| ≤30% | 239 | 88.20 | 431 | 71.00 | 41 | 64.10 | 711 | 72.90 | |
| Total | 271 | 100 | 607 | 100 | 64 | 100 | 942 | 100 | |
|
| |||||||||
| ER | |||||||||
| Positive | 372 | 76.40 | 517 | 72.30 | 175 | 72.30 | 1064 | 77.30 | |
| Negative | 115 | 23.60 | 158 | 27.70 | 67 | 27.70 | 340 | 22.70 | |
| Total | 487 | 100 | 675 | 100 | 242 | 100 | 1404 | 100 | |
|
| |||||||||
| HER2 | |||||||||
| Positive | 91 | 23.80 | 89 | 14.00 | 68 | 25.50 | 248 | 19.10 | |
| Negative | 292 | 76.20 | 547 | 86.00 | 199 | 74.50 | 1038 | 80.90 | |
| Total | 383 | 100 | 636 | 100 | 267 | 100 | 1286 | 100 | |
|
| |||||||||
| Age | |||||||||
| <40 | 160 | 24.90 | 135 | 20.90 | 88 | 31.10 | 383 | 19.80 | |
| =40–50 | 193 | 30.00 | 236 | 36.50 | 100 | 35.30 | 529 | 31.90 | |
| ≥50 | 290 | 45.10 | 275 | 42.60 | 95 | 33.60 | 660 | 48.30 | |
| Total | 643 | 100 | 646 | 100 | 283 | 100 | 1572 | 100 | |
|
| |||||||||
| Histology | |||||||||
| IDC | 591 | 90.90 | 449 | 64.50 | 161 | 62.60 | 1201 | 74.90 | |
| ILC | 25 | 3.80 | 83 | 11.90 | 35 | 13.60 | 143 | 8.90 | |
| IDC + DCIS | 23 | 3.50 | 93 | 13.40 | 39 | 15.20 | 155 | 9.70 | |
| IDC + ILC | 2 | 0.30 | 60 | 8.60 | 19 | 7.40 | 81 | 5.10 | |
| Others | 9 | 1.40 | 11 | 1.60 | 3 | 1.20 | 23 | 1.40 | |
|
| |||||||||
| Adjuvant therapy | |||||||||
| CT + HT | 245 | 68.40 | 435 | 72.00 | 166 | 70.00 | 846 | 70.60 | |
| HT alone | 33 | 9.20 | 19 | 3.10 | 6 | 2.50 | 58 | 4.80 | |
| CT alone | 80 | 22.30 | 150 | 24.80 | 65 | 27.40 | 295 | 24.60 | |
| Total | 358 | 100 | 604 | 100 | 237 | 100 | 1199 | 100 | |